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This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum may lead to acne that is severe. If left untreated, severe acne may cause scarring that is permanent.

OTHER USES: This section contains uses of this drug being not detailed in the approved professional labeling for the drug but that may be prescribed by your health care pro. Make use of this drug for a state of being which is placed in this section as long as it has been so prescribed by your wellness care expert.

This medication can also be used to deal with a certain type of cancer (neuroblastoma).

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Read the Medication Guide supplied by your pharmacist you get a refill before you start using isotretinoin and each time. Read and sign a Patient Information/Informed Consent form before you start taking this medication. If you have any relevant questions about isotretinoin, consult your physician or pharmacist before taking the medicine.

Swallow capsules whole. Never crush or chew them. Isotretinoin is often taken twice daily for 15-20 weeks, or as directed by your medical practitioner. Directions for many generic forms of isotretinoin state that it must be taken with meals. However, the FDA has indicated that the Absorica brand name might be taken with or without food. Food helps increase absorption of this drug into your bloodstream. Ask your doctor or pharmacist for more information. Take this drug with a glass that is full of, and do not lie down for 10 moments after taking it.

The dosage is based on your condition that is medical, and response to treatment.

Your acne may worsen throughout the very first day or two of using this drug, also it may use up to 1-2 months before you spot the benefit that is full of medication. If severe acne returns, a second course of treatment may be started after you have stopped taking the drug for 2 months. The manufacturer will not recommend long-term use of isotretinoin. Do not take more than the recommended dose.

Since this drug is absorbed through the skin and lungs and may damage an unborn baby, ladies who are pregnant or who can become pregnant should not handle this medicine or inhale the dust from the capsules.

Unwanted Effects

Dry lips and mouth, minor inflammation of the eyelids or lips, crusty skin, nosebleeds, upset belly, or thinning of locks may take place. If some of these effects persist or worsen, tell your pharmacist or doctor quickly.

To relieve mouth that is dry suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute.

Keep in mind that your particular doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious adverse effects.

Tell your physician right away if you have actually some of these not likely but serious adverse effects: mental/mood changes (e.g., depression, aggressive or violent behavior, plus in rare instances, thoughts of suicide), tingling feeling in the skin, quick/severe sunburn (sunlight sensitiveness), back/joint/muscle discomfort, indications of disease (age.g., fever, persistent sore throat), painful swallowing, peeling epidermis on palms/soles.

Isotretinoin may rarely cause disease associated with pancreas (pancreatitis) that may rarely be fatal. Stop taking this medication and inform your medical practitioner immediately if you develop: serious stomach pain, severe or persistent nausea/vomiting.

Stop taking this medication and tell your doctor appropriate away if you develop these not likely but very serious unwanted effects: severe headache, vision modifications, ringing ears, hearing loss, chest pain, yellowing eyes/skin, dark urine, severe diarrhea, rectal blood.

A very severe allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any observeable symptoms of a serious allergic effect, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a list that is complete of adverse effects. If you notice other effects not listed above, contact your pharmacist or doctor.

Into the US -

Call your doctor for medical advice about side effects. You may possibly report adverse effects to FDA at 1-800-FDA-1088 or at

In Canada - Phone your doctor for medical advice about adverse effects. You may possibly report effects that are side Health Canada at 1-866-234-2345.


Before taking isotretinoin, tell your medical professional or pharmacist in the event that you are allergic to it; or to vitamin A-related drugs (other retinoids such as tretinoin); or if you have any other allergies. This product may contain inactive ingredients (such as soybean, parabens), which can cause allergy symptoms or other dilemmas. Some individuals who are allergic to peanuts may also be allergic to soy. Speak to your pharmacist for additional information.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, family or personal history of high blood fats (triglycerides), family or personal history of psychiatric disorders (including depression), liver disease, obesity, eating disorders (e.g., anorexia nervosa), alcohol abuse, pancreatitis, bone loss conditions (e.g., osteoporosis/osteomalacia, decreased bone density).

Do not donate blood after you stop taking it while you are taking isotretinoin and for at least 1 month.

This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when in the open air.

Isotretinoin make a difference your vision night. Do not drive, use machinery, or do any activity that requires clear vision after dark until you are sure you can perform such activities safely.

You may not tolerate them as well as usual while using this medication if you wear contact lenses. Contact your medical practitioner for more information.

Don't have procedures that are cosmetic smooth your skin (e.g., waxing, laser, dermabrasion) during and for 6 months after isotretinoin therapy. Skin scarring may occur.

Avoid making use of alcohol while taking this medication because it may increase the risk of certain side-effects (age.g., pancreatitis).

Restricted information suggests isotretinoin may cause some bone loss effects. Therefore, playing contact or repetitive impact sports (e.g., football, basketball, soccer, tennis) may result in bone problems, including an increased risk of broken bones. Limited information also suggests isotretinoin may stop normal growth in some children (epiphyseal dish closure). Consult with your physician for more details.

Care is recommended when making use of this medication into the elderly because they might be more painful and sensitive to its effects, particularly the effects on bones.

Caution is preferred when working with this drug in young ones because they might be more responsive to its effects, especially back/joint/muscle pain.

This drug ought not to be used during maternity or by people who may become pregnant during treatment. You may be pregnant, inform your doctor right away if you become pregnant or think. See also Warning section.

Since this drug are absorbed through the skin and lungs and may harm an unborn baby, females who're pregnant or who may become expecting should not handle this medication or breathe the dust from the capsules.

You'll want two pregnancy that is negative before starting this medication. You must have a monthly pregnancy test during treatment with isotretinoin. If the test is positive, you must stop taking this medication and consult your physician right away.

It is unknown if this medication passes into breast milk. However, similar drugs pass into breast milk. Breast-feeding while using this drug is not recommended. Consult your medical practitioner before breast-feeding.

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