This medication is utilized to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to acne that is severe. If left untreated, severe acne may cause permanent scarring.

DIFFERENT USES: This area contains uses of this drug which can be not listed in the approved professional labeling for the drug but which will be prescribed by your wellbeing care professional. Use this drug for a state of being which is listed in this section only if it has been so prescribed by your wellness care expert.

This medicine may also be used to deal with a certain type of cancer (neuroblastoma).

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Read the Medication Guide provided by your pharmacist you get a refill before you start using isotretinoin and each time. Read and sign a Patient Information/Informed Consent form before you start taking this medication. If you have any relevant questions about isotretinoin, consult with your physician or pharmacist before taking the medication.

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Swallow capsules whole. Usually do not crush or chew them. Isotretinoin is frequently taken twice daily for 15-20 weeks, or as directed by your physician. Directions for most generic forms of isotretinoin state that it should really be taken with meals. Nevertheless, the FDA has indicated that the Absorica brand might be taken with or without food. Food helps increase absorption of this drug into your bloodstream. Ask your pharmacist or doctor for lots more information. Take this drug with a glass that is full of, and do not lie down for 10 minutes after taking it.

The dosage is founded on your medical condition, weight, and response to treatment.

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Your acne may worsen throughout the first day or two of taking this medication, also it may take up to 1-2 months before you spot the benefit that is full of medication. If severe acne returns, a second course of treatment may be started after you have stopped taking the drug for 2 months. The manufacturer doesn't suggest long-term use of isotretinoin. Never take more than the recommended dose.

Since this drug could be consumed through the skin and lung area and may damage an unborn baby, ladies who are pregnant or who can become pregnant should perhaps not handle this medicine or inhale the dust from the capsules.

Negative Effects

Dry lips and mouth, minor inflammation of the eyelids or lips, crusty skin, nosebleeds, upset belly, or thinning of locks may occur. If any of these effects persist or aggravate, tell your doctor or pharmacist immediately.

To relieve mouth that is dry suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or make use of a saliva substitute.

Keep in mind your medical practitioner has recommended this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your physician right away in the event that you have any of these not likely but side that is serious: mental/mood changes (e.g., depression, aggressive or violent behavior, as well as in uncommon instances, thoughts of committing suicide), tingling feeling in your skin, quick/severe sunburn (sun sensitivity), back/joint/muscle discomfort, signs of disease (age.g., fever, persistent sore throat), painful swallowing, peeling skin on palms/soles.

Isotretinoin may hardly ever cause disease for the pancreas (pancreatitis) that may rarely be deadly. Stop taking this medication and inform your physician immediately if you develop: serious stomach pain, severe or persistent nausea/vomiting.

Stop taking this medicine and tell your doctor right away if you develop these not likely but very serious unwanted effects: severe hassle, eyesight changes, tinnitus, hearing loss, chest discomfort, yellowing eyes/skin, dark urine, severe diarrhea, rectal blood.

A very severe reaction that is allergic this drug is rare. However, seek immediate attention that is medical you notice any observeable symptoms of a significant allergic response, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, difficulty breathing.

This just isn't a complete list of possible side effects. If you notice other effects not listed above, contact your pharmacist or doctor.

Within the US -

Call your medical professional for medical advice about side-effects. You'll report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Phone your medical professional for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

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Before taking isotretinoin, tell your physician or pharmacist if you are allergic to it; or to vitamin A-related drugs (other retinoids such as tretinoin); or if you have any other allergies. This product may contain inactive ingredients (such as soybean, parabens), which can cause allergies or other issues. Some people who are sensitive to peanuts may also be allergic to soy. Confer with your pharmacist for additional information.

Anorexia nervosa), alcohol abuse, pancreatitis, bone loss conditions (e.g., osteoporosis/osteomalacia, decreased bone density) before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, family or personal history of high blood fats (triglycerides), family or personal history of psychiatric disorders (including depression), liver disease, obesity, eating disorders ( e.g..

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Do not donate blood while you are taking isotretinoin and for at least 1 month after you stop taking it.

This medication might make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when out-of-doors.

Isotretinoin can affect your night vision. Do not drive, use machinery, or do any activity that requires clear vision after dark you can perform such activities safely until you are sure.

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If you wear contact lenses, you may not tolerate them as well as usual while using this medication. Contact your doctor for lots more information.

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Don't have procedures that are cosmetic smooth your skin (e.g., waxing, laser, dermabrasion) during and for 6 months after isotretinoin therapy. Skin scarring may occur.

Avoid the application of alcohol while taking this medication because it may increase the risk of certain unwanted effects (age.g., pancreatitis).

Limited information implies isotretinoin may cause some bone loss effects. Therefore, playing contact or repetitive impact sports (e.g., football, basketball, soccer, tennis) may result in bone problems, including an increased risk of broken bones. Limited information also suggests isotretinoin may stop growth that is normal some children (epiphyseal plate closure). Consult with your doctor for more details.

Care is preferred when utilizing this medication in the elderly because they may be more delicate to its results, particularly the effects on bones.

Care is recommended when working with this drug in children because they may be more sensitive to its results, specially back/joint/muscle pain.

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This medication must not be used during maternity or by those that may become pregnant during treatment. If you become pregnant or think you may be pregnant, inform your doctor right away. See section that is also warning.

Since this drug is absorbed through your skin and lungs and may harm an baby that is unborn women who are pregnant or who may become expecting must not handle this medication or breathe the dust from the capsules.

You'll want two pregnancy that is negative before starting this medication. You must have a monthly pregnancy test during treatment with isotretinoin. If the test is positive, you must stop taking this medication and check with your doctor right away.

It's unknown if this medication passes into breast milk. Nonetheless, similar medications pass into breast milk. Breast-feeding while by using this drug is not advised. Consult your doctor before breast-feeding.

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