Clomipramine is used to take care of obsessive disorder that is compulsiveOCD). It helps decrease persistent/unwanted thoughts (obsessions), and it assists in easing the urge to perform duplicated tasks (compulsions such as hand-washing, counting, checking) that interfere with day to day living.
This medication belongs to a class of medications called antidepressants that are tricyclic. It works by restoring the balance of certain substances that are naturalserotonin, amongst others) in the brain.
DIFFERENT USES: This area contains uses of this drug that are perhaps not placed in the approved professional labeling for the drug but that could be prescribed by your medical care professional. Utilize this drug for a condition that is detailed in this part only if it was so prescribed by the health care professional.
This medication has additionally been utilized to treat depression, panic assaults, and pain that is ongoing.
Read the Medication Guide available from your pharmacist. Consult with your doctor or pharmacist if you have any questions.
Take this medication by mouth with or without food as directed by your physician. To lessen negative effects such as stomach upset, clomipramine may be started at a dose that is low given in several doses during the day with meals, and slowly increased as your body gets used to it. For you, the total dose can be taken once daily, usually at bedtime to prevent daytime drowsiness or as directed by your doctor after you have reached the best dose. Frequently, the dose that is daily maybe not be more than 250 milligrams for grownups and 200 milligrams for children and teenagers.
Follow your doctor's guidelines very carefully. Never take just about medication or frequently take it more than prescribed. Your condition will not improve any faster and your risk of side effects such as for instance seizures may be increased. Dosage is dependant on your medical condition and response to therapy.
Avoid eating drinking or grapefruit grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your doctor or pharmacist for additional information.
Make use of this medication regularly in order to obtain the benefit that is most from it. Continue to take it even if you feel well. To help you remember, use it at the same time(s) each time.
Usually do not suddenly stop using this medication without consulting your physician. Some conditions may be even worse when the drug is suddenly stopped. You could experience sweating, dizziness, sickness, vomiting, headache, or irritability if you unexpectedly stop taking this drug. Your dose may need to be gradually decreased.
It may just take 2 to 3 days or longer ahead of the complete effects of this medication are noticed. Inform your doctor if the condition persists or if it worsens.
See section that is also warning.
Dizziness, drowsiness, dry mouth, constipation, stomach upset, nausea, vomiting, changes in appetite/weight, flushing, sweating, tiredness and blurred vision may occur. Anxiety signs may temporarily aggravate when you initially start taking clomipramine. If any of these effects persist or worsen, notify your pharmacist or doctor quickly.
To alleviate mouth that is dry suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water or utilize a saliva replacement.
To prevent constipation, maintain a meal plan adequate in fiber, drink plenty of water, and exercise. If you feel constipated while making use of this drug, check with your pharmacist for aid in selecting a laxative (e.g., stimulant-type with stool softener).
Remember that your physician has recommended this medication she has judged that the benefit to you is greater than the risk of side effects because he or. Many people using this medication do not have side that is serious.
Tell your doctor right away if some of these unlikely but serious side effects occur: mental/mood modifications (e.g., confusion, despair, memory problems), enlarged/painful breasts, unwanted breast milk manufacturing, irregular/painful menstrual durations, muscle stiffness, ringing into the ears, sexual problems (e.g., reduced sexual ability, changes in desire), shakiness (tremors), numbness/tingling of this hands/feet, difficulty urinating.
Tell your physician right away if any of these rare but really adverse that is serious occur: easy bruising/bleeding, signs of infection (e.g., fever, persistent sore throat), unusual/uncontrolled movements (especially regarding the tongue/face/lips), serious stomach/abdominal pain, dark urine, yellowing of eyes/skin.
This medication may increase serotonin and hardly ever cause a very serious condition called serotonin syndrome/toxicity. The risk increases you take if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs. Get medical help right away in the event that you develop a number of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscle tissue, unexplained fever, uncommon agitation/restlessness.
Get medical help right away if you have very severe side effects, including: black stools, upper body pain, fainting, slow/fast/irregular heartbeat, seizures, vomit that looks like coffee grounds, eye pain/swelling/redness, vision modifications (such as seeing rainbows around lights through the night).
An extremely severe allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious reaction that is allergic: rash, itching/swelling (especially for the face/tongue/throat), severe dizziness, difficulty breathing.
This is not a list that is complete of adverse effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the usa -
Phone your physician for medical advice about adverse effects. You may report adverse effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about adverse effects. You may report effects that are side Health Canada at 1-866-234-2345.
Before taking clomipramine, tell your medical practitioner or pharmacist if you have any other allergies if you are allergic to it; or to other tricyclic antidepressants (e.g., imipramine, nortriptyline); or. This product may contain inactive ingredients, which can cause allergies or other issues. Talk to your pharmacist for more details.
Before applying this medicine, tell your doctor or pharmacist your medical background, especially of: blood problems (age.g., purpura, thrombocytopenia), difficulty in breathing (e.g., asthma, chronic bronchitis), personal or genealogy and family history of glaucoma (angle-closure type), eating disorders (age.g., bulimia), heart dilemmas (e.g., arrhythmias, coronary artery disease, recent heart attack), intestinal dilemmas (e.g., chronic constipation, ileus), liver problems, kidney problems, personal or family history of other mental/mood conditions (e.g., manic depression, schizophrenia), history of hospitalization for a very severe response to specific medicines (neuroleptic cancerous problem), heartburn/stomach acid within the esophagus (e.g., due to hiatal hernia), seizures, overactive thyroid (hyperthyroidism), trouble urinating (urinary retention, enlarged prostate), any condition that may raise your risk of seizures (e.g., alcohol/sedative dependency, use of electroconvulsive therapy, brain injury/disease), specific kinds of tumors (e.g., pheochromocytoma, neuroblastoma).
Clomipramine may cause a disorder that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical help immediately.
The threat of QT prolongation are increased if you have actually certain medical conditions or are using other drugs that might cause QT prolongation. Before using clomipramine, tell your doctor or pharmacist of the many drugs you take and when you have any one of the next conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).
Low levels of potassium or magnesium in the bloodstream may also increase your risk of QT prolongation. This risk may increase if you have conditions such as severe sweating, diarrhea, or vomiting if you use certain drugs (such as diuretics/"water pills") or. Talk to your physician about making use of clomipramine safely.
This drug can make you dizzy or drowsy or cause temporary blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision you can perform such activities safely until you are sure. Limit beverages that are alcoholic.
To diminish dizziness and lightheadedness, get up slowly when increasing from a seated or position that is lying.
Before having surgery, tell your dentist or doctor that you're taking this medication.
Caution is recommended when working with this medication in kids who take part in active sports as it may increase the risk of heart problems. (See also the Warning section.)
Older adults may be more painful and sensitive to your relative negative effects of this medication, especially bleeding, confusion, dizziness, and QT prolongation (see above).
This medication should be used only when plainly needed during pregnancy. Newborns exposed to clomipramine during pregnancy may experience withdrawal symptoms or unwanted effects. Inform your doctor immediately if you notice jitteriness, shaking, feeding problems, fast breathing, or seizures in your newborn.
Since untreated mental/mood problems (such as for instance obsessive compulsive disorder, depression, panic attack) can be a serious condition, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.
This drug passes into breast milk and may have undesirable effects on a nursing baby. Consult with your doctor before breast-feeding.
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