See section that is also warning.
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This medication is used to treat certain mental/mood disorders (schizophrenia, schizoaffective disorders). Clozapine is a medication that is psychiatricanti-psychotic type) that actually works by helping to restore the balance of certain natural substances (neurotransmitters) into the brain.
Clozapine decreases hallucinations and helps in avoiding suicide in people who are most likely to try to harm themselves. It will help you to clearly think more and absolutely about your self, feel less nervous, and take part in everyday life.
If you are using the liquid form of this medication, read the Patient Suggestions Leaflet if available from your pharmacist before you start taking clozapine and each time you get a refill. For those who have any relevant concerns, ask your doctor or pharmacist.
Take this medicine by mouth with or without food, as directed by your doctor. If you're taking the pills that dissolve in the lips, remove each tablet carefully from the blister pack immediately before taking your dose. Allow the tablets to dissolve on your tongue and swallow. You do not need to take the dissolving tablets with water. Discard any dissolving tablets that are previously subjected to air due to opened/damaged packaging. Do not save them for your next dose.
If you use the form that is liquid of medication, shake the bottle well for 10 seconds before each use. Carefully measure the dose using a measuring device/spoon that is special. Do not use children spoon because may very well not get the dose that is correct.
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You should begin to take this drug at a low dose, increasing your dose slowly, to lessen side effects such as dizziness, drowsiness and seizures. Follow your doctor's instructions exactly. Your dosage is based on your condition that is medical and to therapy. Since clozapine can cause a decrease in white blood cells, you will have to get blood tests done regularly as directed. Be sure to keep all appointments of these laboratory tests. (See also Notes section.)
You were on (see Missed Dose section) if you miss your doses for longer than a day or two, consult your doctor for a new schedule to get back to the dose. Use this medication regularly in order to get the most benefit from this. To simply help you keep in mind, utilize it at the time( that is same) each day.
Do not stop taking clozapine without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. Also, you might experience symptoms such as severe sweating, headache, sickness, vomiting, and diarrhea. To avoid these signs while you're stopping therapy with this drug, your doctor may lessen your dosage slowly. Check with your doctor or pharmacist for more details. Report any new or worsening symptoms right away.
It usually takes several weeks prior to the full benefit of this medication takes effect. Inform your physician if the condition persists or worsens.
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See also Warning section.
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Drooling, drowsiness, dizziness, headache, shaking (tremor), vision problems (e.g., blurred vision), weight gain, and constipation may occur. Many of these effects (especially drowsiness) lessen as your body gets used to the medication. If any of these effects persist or worsen, contact your pharmacist or doctor promptly.
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To stop constipation, keep a meal plan adequate in fiber, drink plenty of water, and exercise. If you become constipated while using the this medication, check with your pharmacist for help in selecting a laxative (age.g., stimulant-type with stool softener).
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Remember that your doctor has prescribed this medication she has judged that the benefit to you is greater than the risk of side effects because he or. Many people using this medication do not have serious side effects.
This medication may make your blood rarely sugar level rise, which can cause or worsen diabetes. Rarely, very serious conditions such as diabetic coma may occur. Tell your doctor straight away if you develop symptoms of high blood glucose, such as increased thirst and urination. In the event that you already have diabetes, make sure to check your bloodstream sugars regularly. Your doctor may have to adjust your diabetes medication, exercise program, or diet.
This drug might also cause significant weight gain and an increase in your cholesterol (or triglyceride) levels. These effects, along side diabetes, may increase your risk for developing heart illness. Talk about the dangers and advantages of therapy with your doctor.
Tell your physician right away when you have any serious side effects, including: facial/muscle twitching, seizures, uncontrollable movements.
Get medical help right away if you have any really severe side results, including: severe dizziness, fainting, mental/mood changes, trouble respiration with workout, sudden weakness, pain/redness/swelling of the arms/legs, persistent nausea/vomiting, stomach/abdominal pain, yellowing of eyes/skin.
This medicine may seldom cause a really condition that is serious neuroleptic malignant syndrome (NMS). Get medical help right away if you have of the following symptoms: fever, muscle stiffness/pain/tenderness/weakness, severe tiredness, serious confusion, sweating, fast/irregular heartbeat, dark urine, improvement in the number of urine.
A really serious reaction that is allergic this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious reaction that is allergic include: rash, itching/swelling (especially of the face/tongue/throat), serious dizziness, trouble breathing.
This is simply not a list that is complete of side effects. If you notice other effects not listed above, contact your pharmacist or doctor.
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Call your doctor for medical advice about part effects. You may report side effects to Food And Drug Administration at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You'll report side effects to Health Canada at 1-866-234-2345.
See also Warning and Side Effects sections.
Before taking clozapine, tell your doctor or pharmacist in the event that you have any other allergies if you are allergic to it or. This product may contain inactive ingredients, which may cause allergic reactions or other issues. Confer with your pharmacist for additional information.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: history of bloodstream disorders (such as leukemia, low white blood cell count), bowel problems (such as paralytic ileus, cranky bowel problem ), difficulty in breathing, diabetes/family history of diabetes, high cholesterol/triglyceride levels, glaucoma, heart problems, kidney problems, liver problems, obesity/family history of obesity, seizures, difficulty urinating (such as prostate problems).
Clozapine may cause a disorder that impacts the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other signs (such as serious dizziness, fainting) that need medical attention appropriate away.
The possibility of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that could affect one's heart rhythm. Before making use of clozapine, tell your physician or pharmacist of all of the the drugs you take and for those who have any of the following conditions: certain heart dilemmas (heart failure, slow heartbeat, QT prolongation into the EKG), genealogy and family history of certain heart disease (QT prolongation in the EKG, unexpected cardiac death).
Lower levels of potassium or magnesium in the blood may increase your risk also of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Confer with your doctor about making use of clozapine safely.
This drug can make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit beverages that are alcoholic.
Tell your physician if you are a descendent of Ashkenazi Jews because you may be at a higher risk for a drop in your white blood cells.
Before having surgery, tell your doctor or dentist that you're making use of this medication.
Liquid items or dissolving tablets may contain sugar and/or aspartame. Liquid products may also contain alcohol. Caution is encouraged if you have diabetes, liver disease, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet. Ask your doctor or pharmacist about applying this product safely.
Older grownups may be more sensitive to the relative side aftereffects of this drug, particularly constipation, dizziness, and QT prolongation (see above). Dizziness can boost the danger of falling.
During pregnancy, this medicine should be used only when plainly needed. Babies born to moms who used this drug over the last 3 months of pregnancy may rarely develop symptoms including muscle stiffness or shakiness, drowsiness, feeding/breathing difficulties, or constant crying. If you notice any of these symptoms in your newborn especially during their month that is first the doctor straight away.
Since untreated mental/mood problems (such as schizophrenia, schizoaffective problems) can be a condition that is serious do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.
This medicine may pass into breast milk while having effects that are undesirable a nursing infant. Breast feeding is not advised while taking clozapine. Consult your physician before breast-feeding.
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