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Duloxetine is employed to deal with depression and anxiety. In addition, duloxetine can be used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing discomfort due to health conditions such as for instance arthritis, chronic back discomfort, or fibromyalgia (a condition that causes widespread discomfort).

Duloxetine may improve your mood, rest, appetite, and degree of energy, and decrease nervousness. It may relieve pain because of certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in mental performance.

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OTHER USES: This part contains uses of this drug being not listed in the approved labeling that is professional the drug but that may be prescribed by your health care pro. Utilize this medication for a condition that is listed in this part as long as it was so recommended by your quality of life care professional.

This medication may also be used to help treat other painful nerve conditions (neuropathic pain).

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Read the Medication Guide and, if available, the Patient Information Leaflet supplied by your pharmacist you get a refill before you start using duloxetine and each time. If you have any relevant questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your physician, often 1 or 2 times a day with or without food. If you have nausea, it may help to take this drug with food. Swallow the capsule whole. Usually do not crush or chew the capsule or mix the contents with liquid or food. Doing therefore can release all of the drug at once, increasing the risk of adverse effects.

The dosage is dependant on your age, medical problem and response to treatment. To reduce your risk of side effects, your doctor may direct you to definitely start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Take this medication regularly to get the most benefit from it. To greatly help you remember, take it at the same time(s) each time.

You will need to carry on taking this medication as prescribed even in the event that you feel well. Do not stop taking this medicine without consulting your medical professional. Some conditions could become worse whenever this drug is suddenly stopped. Additionally, you may experience symptoms such as for instance dizziness, confusion, mood swings, frustration, tiredness, diarrhoea, rest changes, and brief feelings much like electric shock. Your dose may need to be gradually decreased to reduce adverse results. Report any new or symptoms that are worsening away.

Inform your medical professional if your condition persists or worsens.

Part Effects

See section that is also warning.

Sickness, dry mouth, constipation, loss of appetite, tiredness, drowsiness, or increased sweating may occur. If any of these results persist or worsen, tell your medical professional promptly.

Dizziness or lightheadedness may possibly occur, especially once you start that is first increase your dose of this drug. To reduce the risk of dizziness, lightheadedness, or falling, get up slowly when rising from a sitting or position that is lying.

Remember that your medical practitioner has recommended this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This medicine may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the total answers are high.

Inform your doctor right away if any one of these serious part results occur: confusion, easy bruising/bleeding, reduced interest in intercourse, changes in intimate ability, muscle tissue cramps/weakness, shaking (tremor), difficulty urinating, unusual decrease in the amount of urine, signs of liver problems (such as stomach/abdominal pain, persistent sickness, vomiting, yellowing eyes/skin, dark urine).

Get medical help straight away if you have got any very serious side-effects, including: black/bloody stools, vomit that seems like coffee grounds, seizure, attention pain/swelling/redness, vision changes (such as for example seeing rainbows around lights at night, blurred vision).

This medication may increase serotonin and rarely cause an extremely condition that is serious serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take (see Drug Interactions section). Get medical help right away in the event that you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness.

a very serious allergic reaction to this drug is rare. However, get help that is medical away if you notice any symptoms of a significant allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble respiration, skin blisters, mouth sores.

This will be not a complete list of possible side effects. If you notice other effects not listed above, contact your pharmacist or doctor.

In america -

Call your doctor for medical advice about part effects. You may report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Phone your doctor for medical advice about side effects. You'll report effects that are side wellness Canada at 1-866-234-2345.


Before using duloxetine, inform your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, that may cause allergies or other problems. Talk to your pharmacist to get more details.

Before making use of this medicine, inform your doctor or pharmacist your medical history, especially of: personal or family history of psychiatric disorders (such as for example bipolar/manic-depressive disorder), personal or family history of suicide attempts, bleeding dilemmas, personal or household history of glaucoma (angle-closure type), hypertension, kidney disease, liver disease, seizure disorder, stomach problems (such as slow emptying regarding the stomach), use/abuse of alcohol.

This medication may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness you can perform such activities safely until you are sure. Avoid beverages that are alcoholic.

When you have diabetes, duloxetine may impact your blood sugar levels. Check always your blood sugar regularly as directed by your doctor. Your physician may need to adjust your diabetes medication, exercise regime, or diet.

Before having surgery, tell your physician or dentist about all the products you utilize (including prescription drugs, nonprescription drugs, and herbal products).

Older adults may be more sensitive to the relative adverse effects of this drug, especially bleeding, dizziness, lightheadedness, or loss of coordination. Older adults may be more likely also to develop a type of salt imbalance (hyponatremia), particularly when they are taking "water pills" (diuretics). Dizziness, lightheadedness, or loss of coordination can boost the risk of falling.

Children may be more delicate to the relative side effects of this drug, especially loss of appetite and weight loss. Monitor height and weight in children who are taking this drug. See also Warning.

During pregnancy, this medicine should really be used only once clearly needed. It may harm an unborn baby. Also, babies born to mothers who have used this drug during the last 3 months of pregnancy may rarely develop withdrawal symptoms such as feeding/breathing difficulties, seizures, muscle stiffness, or constant crying. In the event that you notice any one of these symptoms in your newborn, tell the doctor promptly.

Since untreated mental/mood issues (such as depression, anxiety) are a condition that is serious do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss the benefits and risks of using this medication during pregnancy with your doctor.

This drug passes into breast milk and might have effects that are undesirable a nursing infant. Consult your medical practitioner before breast-feeding.

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