Duloxetine can be used to deal with depression and anxiety. In addition, duloxetine can be used to aid relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing discomfort due to health conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread discomfort).

Duloxetine may improve your mood, rest, appetite, and degree of energy, and decrease nervousness. It may also relieve pain as a result of certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain substances that are naturalserotonin and norepinephrine) in the brain.

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OTHER USES: This section contains uses of this medication that are maybe not placed in the approved labeling that is professional the medication but that will be prescribed by your health care expert. Make use of this drug for a condition that is listed in this part only when it has been therefore recommended by your wellbeing care professional.

This medication could also be used to help treat other painful nerve conditions (neuropathic pain).

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Read the Medication Guide and, if available, the Patient Information Leaflet supplied by your pharmacist you get a refill before you start using duloxetine and each time. If you have any relevant questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your physician, frequently 1 or 2 times a day with or without food. If you have nausea, it may help to take this drug with food. Swallow the capsule whole. Never crush or chew the capsule or mix the contents with liquid or food. Doing so can release every one of the drug at once, increasing the risk of side effects.

The dosage is dependant on your age, medical condition and reaction to treatment. To cut back your threat of side effects, your doctor may direct you to start this medicine at a dose that is low gradually increase your dose. Follow your doctor's instructions carefully. Take this medication regularly to get the benefit that is most from this. To aid you remember, simply take it at the time( that is same) each day.

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It is critical to continue taking this medicine as prescribed even should you feel well. Do not stop taking this medicine without consulting your medical professional. Some conditions can become worse whenever this drug is unexpectedly stopped. Additionally, you may experience symptoms such as dizziness, confusion, mood swings, frustration, tiredness, diarrhea, rest changes, and brief emotions much like shock that is electric. Your dose may gradually need to be decreased to reduce side results. Report any brand new or symptoms that are worsening away.

Inform your physician should your condition persists or worsens.

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Part Effects

See section that is also warning.

Sickness, dry mouth, constipation, loss of appetite, tiredness, drowsiness, or increased sweating may occur. If any one of these impacts persist or aggravate, tell your medical professional promptly.

Dizziness or lightheadedness may occur, particularly when you start that is first increase your dose of this drug. To reduce the risk of dizziness, lightheadedness, or falling, get up slowly when rising from a sitting or position that is lying.

Remember that your medical practitioner has prescribed this medication she has judged that the benefit to you is greater than the risk of side effects because he or. Many people using this medication do not have side that is serious.

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This medication might raise your blood pressure. Check your blood pressure regularly and tell your doctor if the total answers are high.

Tell your doctor right away if any of these serious part impacts occur: confusion, easy bruising/bleeding, reduced interest in sex, changes in intimate ability, muscle cramps/weakness, shaking (tremor), difficulty urinating, unusual decrease in the amount of urine, signs of liver problems (such as stomach/abdominal pain, persistent nausea, vomiting, yellowing eyes/skin, dark urine).

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Get medical help immediately if you've got any really serious unwanted effects, including: black/bloody stools, vomit that appears like coffee grounds, seizure, eye pain/swelling/redness, vision changes (such as seeing rainbows around lights at night, blurred vision).

This medication may increase serotonin and rarely cause a tremendously serious condition called serotonin syndrome/toxicity. The risk increases you take (see Drug Interactions section) if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs. Get medical help right away in the event that you develop some of the next symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, serious nausea/vomiting/diarrhea, twitching muscle tissue, unexplained temperature, unusual agitation/restlessness.

a really severe reaction that is allergic this drug is rare. However, get medical help right away if you notice any symptoms of a critical allergic effect, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble respiration, skin blisters, mouth sores.

This might be not a complete list of possible side effects. If you notice other effects not listed above, contact your pharmacist or doctor.

In the US -

Phone your doctor for medical advice about part effects. You may report side effects to FDA at 1-800-FDA-1088 or at

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In Canada - Call your doctor for medical advice about part effects. You could report effects that are side Health Canada at 1-866-234-2345.


Before taking duloxetine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain ingredients that are inactive which can cause allergic reactions or other dilemmas. Talk to your pharmacist for more details.

Before applying this medicine, inform your doctor or pharmacist your medical history, especially of: personal or family history of psychiatric disorders (such as for example bipolar/manic-depressive condition), personal or family history of suicide attempts, bleeding issues, personal or family history of glaucoma (angle-closure type), high blood pressure, renal disease, liver disease, seizure condition, belly problems (such as slow emptying associated with stomach), use/abuse of alcohol.

This drug might make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness you can perform such activities safely until you are sure. Avoid beverages that are alcoholic.

When you have diabetes, duloxetine may impact your blood sugar. Always check your blood sugar levels regularly as directed by your doctor. Your doctor may need to regulate your diabetes medication, exercise regime, or diet.

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Before having surgery, tell your medical professional or dentist about all of the services and products you employ (including prescription drugs, nonprescription medications, and herbal products).

Older adults may be more responsive to the relative side effects of this drug, especially bleeding, dizziness, lightheadedness, or loss of coordination. Older adults may also be more likely to develop a kind of salt imbalance (hyponatremia), particularly if they are taking "water pills" (diuretics). Dizziness, lightheadedness, or loss of coordination can boost the risk of falling.

Children may be more sensitive to the relative side effects of this drug, especially loss of appetite and weight loss. Monitor height and weight in children who're taking this drug. See also Warning.

During pregnancy, this medicine must be used only if clearly needed. It may harm an baby that is unborn. Also, babies born to mothers who have used this drug during the last 3 months of pregnancy may rarely develop withdrawal symptoms such as feeding/breathing difficulties, seizures, muscle stiffness, or constant crying. In the event that you notice some of these symptoms in your newborn, promptly tell the doctor.

Since untreated mental/mood issues (such as depression, anxiety) may be a condition that is serious do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss the benefits and risks of using this medication during pregnancy with your doctor.

This drug passes into breast milk and could have undesirable effects on a nursing infant. Consult with your doctor before breast-feeding.

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