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Precautions

Do NOT use Estrace if:

• you are allergic to the ingredient in Estrace
• you are pregnant or suspect you may well be pregnant, have recently given birth or are breast-feeding, or have vaginal bleeding of abnormal or unknown cause
• you might have known or suspected breast cancer (unless directed through your doctor) or else you have cancers which can be estrogen-dependent
• you've blood clots, vein inflammation, or liver disease
• you experienced a recently available stroke or heart attack.

Contact your physician or doctor immediately if these sign up for you.

Some medical ailments may interact with Estrace. Tell a medical expert or pharmacist when you have any health conditions, particularly when any from the following affect you:

• if you are planning to become pregnant
• if you adopt any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• when you have allergies to medicines, foods, or any other substances
• for those who have a family history of cancer of the breast, or perhaps you have breast lumps or disease, or an abnormal mammogram
• for those who have yellowing in the whites in the eyes or skin while pregnant or with past estrogen use, or high blood pressure levels when pregnant (toxemia)
• in case you have a vaginal infection or womb problems (eg, uterine fibroids/endometriosis, abnormal vaginal bleeding, other uterine problems)
• when you have abnormal calcium levels inside the blood, asthma, cancer, certain blood disorder (porphyria), cholesterol or lipid problems, depression, diabetes, epilepsy, excessive fat gain, gallbladder disease, heart disease or any other heart problems, blood pressure, kidney or liver disease, low thyroid hormonal levels, lupus, migraine headaches, pancreas disease, seizures, or yellowing of the skin or eyes
• in case you smoke or will be having surgery.

Some medicines may talk with Estrace. Tell your health care provider if you take another medicines, especially any of the following:

• Blood thinners (eg, warfarin), corticosteroids (eg, prednisone), succinylcholine, or tacrine as their actions and the risk of their unwanted side effects might be increased by Estrace
• Blood thinners (eg, warfarin) his or her effectiveness might be decreased by Estrace
• Barbiturates (eg, phenobarbital), hydantoins (eg, phenytoin), or rifampin because they may decrease Estrace's effectiveness.

This may not be a complete list of all interactions which could occur. Ask your medical provider if Estrace may connect to other medicines that you just take. Check with your health care provider before starting, stop, or change the dose from a medicine.

Important safety information:

• Estrace could potentially cause dizziness. This effect might be worse in case you take it with alcohol or certain medicines. Use Estrace with caution. Do not drive or perform other possible unsafe tasks and soon you know how you react to it.
• Limit alcohol based drinks while you are taking Estrace.
• Estrace could cause dark skin patches on your face (melasma). Exposure to the sun could make these patches darker and you may must avoid prolonged sun damage and sunlamps. Consult your medical professional about the use of sunscreens and protective clothing.
• Estrace may increase the likelihood of blood clots. The risk might be greater in case you smoke (particularly in women much older than 35 yrs . old).
• Contact a medical expert if vaginal bleeding of unknown cause occurs. This could be a sign of a life threatening condition requiring immediate medical help.
• Contact a medical expert if vaginal discomfort occurs or if you suspect you have developed an infection while taking Estrace.
• Follow your doctor's instructions for examining your breasts and report any lumps immediately.
• Additional monitoring of your dose or condition could possibly be necessary in case you are presently taking an azole antifungal (eg, itraconazole), carbamazepine, a macrolide antibiotic (eg, erythromycin), ritonavir, cimetidine, or St. John's wort.
• If you wear contact lenses and also you develop difficulties with them, contact your doctor.
• If you will probably be having surgery or will likely be confined to a chair or bed for a long period of energy (eg, a lengthy plane flight), notify your medical professional beforehand. Special precautions may must be studied during these circumstances if you are taking Estrace.
• Nonprescription therapy to help you prevent bone loss includes a weight-bearing fitness program, in addition to adequate daily calcium and vitamin D intake. Consult your physician or pharmacist for more details.
• Some of such products may contain the dye tartrazine (FD&C Yellow No. 5), which can cause allergies in certain patients. Consult your doctor or pharmacist. If you previously had hypersensitive reactions on the dye tartrazine, contact your doctor or pharmacist to discover if your product you're taking offers the dye tartrazine.
• Estrace may hinder certain lab tests. Be sure your doctor and lab personnel know you take Estrace.
• Diabetes patients - Estrace may affect your blood sugar. Check blood glucose levels levels closely. Ask your physician prior to deciding to alter the dose of the diabetes medicine.
• Lab tests, including physical exams and blood pressure, may be performed as you use Estrace. You should have breast and pelvic exams, plus a Pap test at least once a year. You should also have periodic mammograms as determined through your doctor. Be sure to keep all doctor and lab appointments.
• Estrace mustn't be utilized in children; safety and effectiveness in children have not been confirmed.
• Pregnancy and breast-feeding: Do not use Estrace if you're pregnant. Avoid getting pregnant while you are taking it. If you think you may be pregnant, contact your doctor straight away. Estrace may be found in breast milk. If you are or will be breast-feeding as you use Estrace, check using your doctor. Discuss any possible risks to your baby.