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Uses

INDICATIONS

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Imuran is used to avoid rejection of the transplanted kidney. It is probably the gang of medicines called immunosuppressive agents. Azathioprine will lower the body's natural immunity in patients who receive transplants to stop rejection with the new kidney. It is also used to relieve pain and swelling for patients with rheumatoid arthritis symptoms.

INSTRUCTIONS

Use this medicine exactly as directed because of your doctor. Do not take really it, or less of it, than your medical professional ordered. Taking too much may increase the probability of negative effects, and taking too little is not going to help your problem.

This medicine is sometimes given in addition to other medicines. If you are choosing several medicines together, be sure to learn how to take them during the day. Ask a medical expert that may help you plan a method to make sure you take your medicines on the right times.

Do not stop investing in this medicine without first checking with your physician.

Imuran sometimes causes feeling sick. Taking this medicine after meals or at bed time may lessen stomach upset. Talk to your physician in case you have questions or continue to have difficulties with nausea or vomiting.

If you miss a dose on this medicine, go as quickly as possible. However, whether it is almost time for your forthcoming dose, skip the missed dose and get back to your normal dosing schedule. Do not double doses.

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DOSAGE

The dose of this medicine vary many different patients. Follow your physician's orders or directions for the label. The following information includes exactly the average doses on this medicine. If your dose is different, tend not to change it out unless your doctor informs you for this.

The level of medicine that you simply take depends about the strength from the medicine. Also, the number of doses you take every day, enough time allowed between doses, as well as the amount of time you're taking the medicine depend around the condition that you can are choosing the medicine.
For oral dosage form (tablets):
For kidney transplant rejection:

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For rheumatoid arthritis: 

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STORAGE 

Store the medicine in a very closed container at room temperature, far from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of kids.
Do not keep outdated medicine or medicine no longer needed.
Ask your health care professional the method that you should get rid of any medicine you usually do not use.

Side Effects

Along having its needed effects, medicines may cause some negative effects. Although not all of these unwanted side effects may occur, should they happen they might need medical attention.

Check with your physician immediately if any in the following unwanted effects occur:


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Some negative effects may occur very often do not need medical help. These negative effects may go away during treatment because your body adjusts towards the medicine. Also, your wellbeing care professional just might let you know about ways to stop or reduce some unwanted side effects. Check together with your health care professional if any of the following unwanted side effects continue or are bothersome or if you have any questions about them:
More common
Nausea or vomiting (mild)
swollen joints
Incidence not known
Hair loss or thinning with the hair

Other side effects not listed could also happen in some patients. If you notice another effects, check together with your doctor.

Call a medical expert for medical advice about side effects.

Precautions

If you'll be using this medicine for some time, it is crucial that your physician check you at regular visits for any problems or negative effects that could be brought on by this medicine. Blood tests are usually necesary to check on for unwanted effects.

Using this medicine while you are pregnant can harm your unborn baby. Use an effective kind of contraceptive to keep from getting pregnant. If you think you have conceive while using the this medicine, tell your doctor immediately.

Do not make use of this medicine in case you are also taking mercaptopurine (Purinethol®). Using these medicines together may cause serious negative effects.

If you are utilizing azathioprine for arthritis, be sure your medical professional knows should you received chlorambucil (Leukeran®), cyclophosphamide (Cytoxan®, Neosar®), or melphalan (Alkeran®) to treat your arthritis inside the past. Using azathioprine after these medicines may raise your risk for uncomfortable side effects. Talk to your doctor for those who have questions on this.

This medicine may increase your risk of getting some types of cancer, especially in the skin, lymph system (lymphoma), or blood (leukemia). Talk to your physician if you have concerns about it risk.

Use sunscreen or sunblock lotions with a sun protection factor (SPF) that is at least 15 on a regular basis when you happen to be outdoors. Wear protective clothing and hats, and stay away from direct sunlight between your hours of 10 a.m. and 3 p.m. Avoid sunlamps and tanning beds.

While you are undergoing treatment with azathioprine, and once you stop treatment with it, tend not to have any immunizations (vaccines) without your doctor's approval. Azathioprine may lower your body's resistance and the vaccine may well not work as well or you may get the infection the vaccine is meant to avoid. In addition, you should not be around other persons living in all your family members who receive live virus vaccines because there is a chance they could pass the virus on to you. Some examples of live vaccines include measles, mumps, influenza (nasal flu vaccine), poliovirus (oral form), rotavirus, and rubella. Do not get near them and usually do not stay in the same room together for too long. If you've got questions on this, talk to your physician.

Azathioprine can temporarily lower the number of white blood cells inside your blood, enhancing the probability of getting contamination. It can also lower the volume of platelets, that are needed for proper blood clotting. If this occurs, there are certain precautions you'll be able to take, particularly if your blood count is low, to reduce the chance of infection or bleeding:

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Check with your physician immediately if you have multiple of the symptoms while you are utilizing this medicine: severe nausea / vomiting; diarrhea; fever; rash; a broad a feeling of discomfort or illness; muscle or pain; lightheadedness or dizziness; or unusual tiredness or weakness. These could be symptoms of an serious reaction for the medicine inside your bowel (intestine).

Do not take other medicines unless they've been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamins.

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