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Uses

INDICATIONS

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Keppra is utilized to help remedy partial onset seizures in older adults and kids who are no less than four weeks old.
It can also be used to treat tonic-clonic seizures in grown-ups and youngsters who will be at the very least 6 years, and myoclonic seizures in grown-ups and kids who're a minimum of 12 years.

INSTRUCTIONS

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Take Keppra the same manner prescribed from your doctor. Do not take in larger or smaller amounts and over recommended. Follow the directions on your prescription label.

Your doctor may occasionally improve your dose to ensure that you obtain the best results.

Keppra is generally taken twice every day. Take the medicine concurrently every day. You may take Keppra with or without food.

Measure liquid medicine using a special dose-measuring spoon or medicine cup, not which has a regular table spoon. If you do not use a dose-measuring device, ask your pharmacist first.
Do not crush, chew, or break a controlled release, delayed-release, or extended-release tablet. Swallow it whole. Breaking the pill may cause excessive drug to be removed at one time.

Use Keppra regularly to find the most benefit. Get your prescription refilled prior to deciding to run out of drugs completely.

Do not stop using Keppra without first conversing with your physician, in case you feel fine. You could have increased seizures in case you stop using this medicine suddenly. You might need to use much less prior to deciding to stop the medication completely.

Seizures will often be treated with a combination of different drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions furnished with each medication. Do not alter your doses or medication schedule without your physician's advice. .

Wear a medical alert tag or carry an ID card proclaiming that you are taking Keppra. Any health care provider who treats you have to know that you are taking seizure medication.

To be sure Keppra is not causing harmful effects, your kidney function may need to be tested. Visit your physician regularly.

If you missed a dose - consider the missed dose when you remember. Skip the missed dose if it's almost time for your upcoming scheduled dose. Do not take extra medicine to produce the missed dose.

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DOSAGE

Important Administration Instructions

Keppra is offered orally with or without food. The Keppra dosing regimen is determined by the indication, population, dosage form (tablets or oral solution), and renal function.

Prescribe the oral solution for pediatric patients with bodyweight ≤ 20 kg. Prescribe the oral solution or tablets for pediatric patients with body mass above 20 kg.

When while using oral solution in pediatric patients, dosing is weight-based (mg per kg) by using a calibrated measuring device (not only a household teaspoon or tablespoon).
Keppra tablets needs to be swallowed whole. Keppra tablets really should not be chewed or crushed.

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Pediatric Patients

Treatment ought to be initiated with a daily dose of 14 mg/kg into two divided doses (7 mg/kg twice daily). The daily dose ought to be increased every 2 weeks by increments of 14 mg/kg on the recommended daily dose of 42 mg/kg (21 mg/kg two times a day). In the medical trial, the mean daily dose was 35 mg/kg within this population. The effectiveness of lower doses has not been studied.

Treatment should be initiated with a daily dose of 20 mg/kg by 50 percent divided doses (10 mg/kg twice daily). The daily dose must be increased into two weeks by an increment of 20 mg/kg on the recommended daily dose of 50 mg/kg (25 mg/kg twice daily). If a patient cannot tolerate a day-to-day dose of 50 mg/kg, the daily dose could be reduced. In the clinical study, the mean daily dose was 47 mg/kg with this age bracket.

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Treatment should be initiated with a daily dose of 20 mg/kg by 50 % divided doses (10 mg/kg two tmes a day). The daily dose must be increased every 14 days by increments of 20 mg/kg towards the recommended daily dose of 60 mg/kg (30 mg/kg twice a day). If a patient cannot tolerate a day-to-day dose of 60 mg/kg, the daily dose may be reduced. In the clinical efficacy trial, the mean daily dose was 44 mg/kg. The maximum daily dose was 3000 mg/day.

For Keppra tablet dosing in pediatric patients weighing 20 to 40 kg, treatment should be initiated having a daily dose of 500 mg given as twice daily dosing (250 mg two tmes a day). The daily dose needs to be increased every fourteen days by increments of 500 mg to your maximum recommended daily dose of 1500 mg (750 mg twice daily).

For Keppra tablet dosing in pediatric patients weighing more than 40 kg, treatment must be initiated with a daily dose of 1000 mg/day given as two tmes a day dosing (500 mg two tmes a day). The daily dose must be increased every two weeks by increments of 1000 mg/day to some maximum recommended daily dose of 3000 mg (1500 mg twice daily).


Partial Onset Seizures
Adults 16 Years And Older

In clinical trials, daily doses of 1000 mg, 2000 mg, and 3000 mg, given as twice-daily dosing were proved to be effective. Although in most studies there were a tendency toward greater response with higher dose [see Clinical Studies], an even boost in response with an increase of dose has not been shown.

Treatment ought to be initiated having a daily dose of 1000 mg/day, given as twice-daily dosing (500 mg twice a day). Additional dosing increments may be given (1000 mg/day additional every 14 days) to some maximum recommended daily dose of 3000 mg. Doses greater than 3000 mg/day have been utilized in open-label studies for periods of a few months and longer. There is no evidence that doses in excess of 3000 mg/day confer additional benefit.

Myoclonic Seizures In Patients 12 Years of Age and Older With Juvenile Myoclonic Epilepsy
Treatment must be initiated having a dose of 1000 mg/day, given as twice-daily dosing (500 mg two times a day). Dosage must be increased by 1000 mg/day every 14 days on the recommended daily dose of 3000 mg. The effectiveness of doses lower than 3000 mg/day is not studied.

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Primary Generalized Tonic-Clonic Seizures
Adults 16 Years And Older
Treatment should be initiated with a dose of 1000 mg/day, given as twice-daily dosing (500 mg twice a day). Dosage should be increased by 1000 mg/day every 14 days to the recommended daily dose of 3000 mg. The effectiveness of doses less than 3000 mg/day is not adequately studied.


Pediatric Patients Ages 6 To < 16 Years
Treatment must be initiated with a daily dose of 20 mg/kg into two divided doses (10 mg/kg two times a day). The daily dose ought to be increased every 14 days by increments of 20 mg/kg for the recommended daily dose of 60 mg/kg (30 mg/kg twice a day). The effectiveness of doses below 60 mg/kg/day hasn't been adequately studied. Patients with body mass ≤ 20 kg ought to be dosed with oral solution. Patients with weight above 20 kg may be dosed with either tablets or oral solution. Only whole tablets must be administered.


Adult Patients With Impaired Renal Function
Keppra dosing has to be individualized according on the patient's renal function status.

STORAGE

Store Keppra at room temperature far from moisture, heat, and light.

Side Effects

Get emergency medical help in the event you have all of these signs of a hypersensitive reaction to Keppra: hives; difficult breathing; swelling of the face, lips, tongue, or throat.

Report any new or worsening symptoms to a medical expert, for example: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call a medical expert simultaneously if you have a serious unwanted effect such as:

Less serious Keppra unwanted effects can sometimes include:

This is just not a complete set of unwanted effects yet others may occur. Tell your doctor about any unusual or bothersome side-effect.

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Precautions

You must avoid using Keppra if you are allergic to levetiracetam.

To ensure you can safely take Keppra, tell your medical professional in case you have kidney disease or high blood pressure levels.

You could have thoughts about suicide while investing in this medicine. Tell your doctor should you have signs of depression or suicidal thoughts in the first weeks of treatment, or as soon as your dose is changed.

Your family or other caregivers should also be alert to changes within your mood or symptoms. Your doctor will have to check you at regular visits.

FDA pregnancy category C. It is just not known whether Keppra will harm an developing fetus, but creating a seizure during pregnancy could harm the mother along with the baby. Tell your doctor in case you are pregnant or prefer to conceive while using this medication. Do not start or stop taking Keppra when pregnant without your medical professional's advice. Seizure control is essential in pregnancy. The benefit of preventing seizures may outweigh any risks presented by taking Keppra. Follow your doctor's instructions about taking Keppra if you are pregnant. Levetiracetam can pass into breast milk and may even harm a nursing baby. You should not breast-feed while you're using Keppra. Do not give this medication to some child minus the advice of your doctor. Your child's dose needs derive from age and weight. The child should remain under the care of a doctor while employing this medicine.

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Do not stop using Keppra without first conversing with your doctor, in case you feel great. You could possibly have increased seizures if you stop using Keppra suddenly. You might need to use much less prior to deciding to stop the medication completely.

You could have thoughts about suicide while taking Keppra. Your doctor will have to check you at regular visits. Do not miss any scheduled appointments.

Report any new or worsening symptoms to your medical professional, for example: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Wear a medical alert tag or carry an ID card on the grounds that you take Keppra. Any medical treatment provider who treats you need to know that you adopt seizure medication.

Keppra may impair your thinking or reactions. Be careful should you drive or do just about anything that will require you to be alert. Tell your medical professional if you are pregnant or plan to get pregnant while applying this medication. Do not start or stop taking Keppra during pregnancy without a medical expert's advice. Having a seizure while pregnant could harm the two mother and the baby. Seizure control is very important when pregnant as well as the advantages of preventing seizures may outweigh any risks presented by using Keppra.

Avoid drinking alcohol. It can increase some of the unwanted side effects of Keppra and could may also increase the potential risk of seizures. This medication may impair your notions or reactions. Be careful if you drive or do anything that needs one to be alert.

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