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Uses

INDICATIONS

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Meldonium treats heart ischemia and its consequencesis.  It is found in the treatment of brain circulation disorders. Meldonium is believed to enhance Mental Processes (Memory, Learning, Focus, Concentration, Processing of Information) and reduces Fatigue, Increases Motivation & Alertness. Meldonium was made to further improve Athletic Training & Competitive Performance at the same time as microcirculation & Oxygen Delivery.

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Due to its unique mechanism of action Mildronate, depending on the prescribed dose, is widely used for the treatment of different heart and vascular diseases, also as to the improvement of work capacity of healthy people at mental and physical overloads and during rehabilitation period.

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INSTRUCTIONS

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Applied internally.

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• Intellectual and physical stress (including in athletes). Adults – 1 g each day
divided into two 500mg doses. Course of treatment is 10-14 days. If necessary, treatments is repeated in 2-3 weeks.

• Athletes should take 500 mg – 1 g two times a day before training. Duration of
treatment during preparatory period is 2-3 weeks, throughout competition – 10-14 days.

• Cardiovascular disease. As part of combined therapy: 500 mg -1 g (1-2 tablets) each day, using whole dose previously or dividing for just two takings. Course of treatment is 4-6 weeks.

• Cardialgia contrary to the background of dyshormonal myocardiodystrophy – 500 mg per day. Course of treatment is 12 days.

• Disturbed cerebral circulation. In treatment after removal of acute disorders: 500 mg – 1 g daily, taking the whole dose in the past or dividing it for just two takings. In case of chronic disorders: 500 mg per day. General treatment is 4-6 weeks. Recurrent courses (usually 2-3 times a year) might be taken after consulting a health care provider.

• Diseases of peripheral arteries. 500 mg twice daily.

• Abstinence syndrome in case of chronic alcoholism. 500 mg 4 times each day. Course of treatment is 7-10 days.

• Maximum daily dose is 2000 mg.


Please talk to your physician ahead of using this or any other nutritional supplements or medications.

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DOSAGE

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Please consult a physician regarding the required dosage.

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Overdosage
There isn't data of cases of Meldonium overdosage. The drug is low-toxic.

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STORAGE 

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Keep far from sunshine.
Keep locked and far from children.
Store in dry place at room temperature.
Do not exceed storage temperature more than 25 C

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Side Effects

Rarely - allergy symptoms (redness, rash, itching, oedema), at the same time as dyspepsia, tachycardia, excitement, changes of arterial pressure.

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Precautions

Contraindications:

Hypersensitivity, increased intracranial pressure (in violation in the venous outflow, intracranial tumors).

Restrictions:

Pregnancy, lactation, children under 18 (capsule, injectable solution) or 12 years (syrup), since safety and efficacy are not determined.

Pregnancy and breast-feeding:

Not recommended during pregnancy (safety weren't proven). At the time of treatment should stop breastfeeding (known perhaps the breast milk gets).

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Interaction with other drugs and other kinds of interaction

The drug could possibly be combined with antianginal agents, anticoagulants and antiaggregants, antiarrhythmic drugs, diuretics, and bronchial spasmolytics. It intensifies the action of coronary vasodilating drugs, some hypotensive agents, and cardiac glycosides. Taking into consideration the possible continuing development of mild tachycardia and arterial hypotension, care must be taken when combining the drug with nitroglycerin, nifediphine, alpha-adrenoceptor blockers, hypotensive agents and peripheral vasodilators.

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