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Mestinon (Pyridostigmine) affects chemicals in the body which can be mixed up in communication between nerve impulses and muscle movement.

Pyridostigmine is used to help remedy the the signs of myasthenia gravis. It is also found in military personnel who have been exposed to nerve gas.

Pyridostigmine doubles for purposes not listed with this medication guide.

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Take exactly as prescribed because of your doctor. Do not take in larger or smaller amounts and for more than recommended. Follow the directions on your prescription label.
Take this medicine with food or milk if it upsets your stomach. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking or opening the pill could cause excessive drug to be removed at once.

Measure liquid medicine having a special dose measuring spoon or medicine cup, not having a regular table spoon. If you do not have a dose measuring device, ask the pharmacist for starters.

The amount and timing of the medicine is very important on the success of one's treatment. Carefully follow a medical expert's instructions about how exactly much medicine to consider then when to take it.

Your doctor may occasionally make positive changes to dose to ensure that you receive the best results. You may be motivated to keep a daily record of when you took each dose and the way long the consequences lasted. This will help your doctor determine if your dose has to be adjusted.
If you need surgery, tell the surgeon ahead of time you are using pyridostigmine. You may need to stop using the medicine for a short time. Store at room temperature faraway from moisture and also heat.


Take the medicine as prescribed by your doctor.

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Keep the tablets inside their original container, combined with the canister of moisture-absorbing preservative that comes with this medicine.


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Active ingredient: Pyridostigmine

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Side Effects

Get emergency medical help in case you have any of these warning signs of a hypersensitive reaction: hives; lack of breath; swelling of the face, lips, tongue, or throat. Stop using pyridostigmine and call a medical expert at the same time in case you have all of these serious side effects:

extreme muscle weakness, muscle twicthing;

slurred speech, vision problems;

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severe vomiting or diarrhea;

cough with mucus;

confusion, anxiety, panic attacks;

seizure (convulsions); or

worsening or no improvement inside your signs of myasthenia gravis.

Less serious negative effects can sometimes include:

cold sweat, pale skin;

urinating more than usual;

watery eyes;

mild nausea, vomiting, or upset stomach;

warmth or tingly feeling; or

mild rash or itching.

This is just not a complete listing of side effects while others may occur. Call your doctor for medical advice about side effects.

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You should avoid using pyridostigmine if you're allergic to it, or if you possess a bladder or bowel obstruction.

To ensure you can safely take pyridostigmine, tell a medical expert for those who have these other concerns:


kidney disease;

an ulcer or any other serious stomach disorder;

high hypertension, heart problems;

overactive thyroid; or

a good reputation for seizures.

It just isn't known whether pyridostigmine will harm an developing fetus. Tell your doctor if you are pregnant or want to get pregnant while using prescription drugs. It is just not known whether pyridostigmine passes into breast milk or whether or not this could harm a nursing baby. Do not use prescription drugs without telling your medical professional should you be breast-feeding a baby.

Drugs interaction 

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Tell your medical professional about all the other medicines you employ, especially:

atropine (Atreza, Sal-Tropine);

belladonna (Donnatal, among others);

benztropine (Cogentin);

clidinium (Quarzan);

clozapine (Clozaril, FazaClo);

dimenhydrinate (Dramamine);

methscopolamine (Pamine), scopolamine (Transderm Scop);

glycopyrrolate (Robinul);

mepenzolate (Cantil);

bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);

bronchodilators like ipratropium (Atrovent) or tiotropium (Spiriva);

cold medicine, allergy medicine, or sleeping pills that contain an antihistamine for example diphenhydramine (Tylenol PM) or doxylamine (Unisom);

heart rhythm medication such as quinidine (Quin-G), procainamide (Procan, Pronestyl), disopyramide (Norpace), flecaininde (Tambocor), mexiletine (Mexitil), propafenone, (Rythmol), while others;

irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Hyomax), or propantheline (Pro Banthine);

medicine to deal with Alzheimer's dementia, including donepezil (Aricept), rivastigmine (Exelon), or tacrine (Cognex); or

a steroid including betamethasone (Celestone) or dexamethasone (Cortastat, Dexasone, Solurex, DexPak).

This list isn't complete along with other drugs may communicate with pyridostigmine. Tell your medical professional about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not find a new medication without telling your physician.

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