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Precautions

Do NOT use Metoclopramide if:

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• you have seizures (eg, epilepsy); bleeding, blockage, or perforation in your stomach or intestines; or tumors on your adrenal gland (pheochromocytoma)

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• you consider cabergoline or pergolide

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• you take medicines, including phenothiazines (eg, chlorpromazine), that might cause extrapyramidal reactions (abnormal, involuntary muscle movements with the head, neck, or limbs). Check with your doctor in case you are unsure if any of your medicines may cause extrapyramidal reactions.

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Contact your medical professional or health care provider right away if all of these connect with you.

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Some health conditions may connect to Metoclopramide. Tell your doctor or pharmacist if you have any health concerns, particularly when any in the following sign up for you:

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• if you're pregnant, likely to become pregnant, or are breast-feeding

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• when you have allergies to medicines, foods, or other substances

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• for those who have a good mental or mood problems (eg, depression) or suicidal thoughts or actions

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• for those who have a good reputation for asthma, heart failure, high blood pressure, diabetes, Parkinson disease, blood problems (eg, porphyria), kidney problems, liver problems (eg, cirrhosis), breast cancer, or lower levels of an enzyme called methemoglobin reductase

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• should you take another type of metoclopramide (eg, syrup, orally disintegrating tablet).

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Some medicines may connect to Metoclopramide. Tell your health care provider if you take another medicines, especially any with the following:

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• Monoamine oxidase inhibitors (MAOIs) (eg, phenelzine) because the likelihood of serious unwanted side effects (eg, high blood pressure, seizures) could possibly be increased

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• Anticholinergic medicine (eg, hyoscyamine) or narcotic pain medicines (eg, codeine) simply because they may decrease Metoclopramide's effectiveness

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• Acetaminophen, benzodiazepines (eg, diazepam), cyclosporine, insulin, levodopa, phenothiazines (eg, chlorpromazine), sedatives (eg, zolpidem), selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), succinylcholine, or tetracycline for the reason that chance of their negative effects could be increased by Metoclopramide

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• Cabergoline, digoxin, or pergolide because their effectiveness might be decreased by Metoclopramide.

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This is probably not a complete report on all interactions that may occur. Ask your health care provider if Metoclopramide may talk with other medicines that you just take. Check with your medical provider before you begin, stop, or alter the dose of the medicine.

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Important safety information:

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• Metoclopramide could cause drowsiness or dizziness. These effects may be worse should you get it with alcohol or certain medicines. Use Metoclopramide with caution. Do not drive or perform other possible unsafe tasks before you recognize how you answer it.
• Do not are drinking alcoholic beverages or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you might be using Metoclopramide without first checking with a medical expert; it may increase their effects. Ask your pharmacist when you have questions on which medicines could potentially cause drowsiness.

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• Do NOT take more than the recommended dose or use Metoclopramide more than 12 weeks without checking along with your doctor.

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• Diabetes patients - Metoclopramide may affect your blood sugar. Check blood glucose levels closely. Ask your medical professional when you change the dose of one's diabetes medicine.

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• Tell your doctor or dentist that you take Metoclopramide before you decide to receive any medical or dental treatments, emergency care, or surgery.

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• Neuroleptic malignant syndrome (NMS) is a possibly fatal syndrome which can be caused by Metoclopramide. Symptoms may include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Contact your medical professional at the same time for those who have any of these symptoms.

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• Some patients who take Metoclopramide may develop muscle movements that they can cannot control. This is more prone to happen in elderly patients, especially women. The chance that will happen or that it'll become permanent is greater in those having Metoclopramide in higher doses and a long time. Muscle problems may also occur after short-term treatment with low doses. Tell your physician at once in case you have muscle problems along with your arms; legs; or maybe your tongue, face, mouth, or jaw (eg, tongue sticking out, puffing of cheeks, mouth puckering, chewing movements) while taking Metoclopramide.

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• Patients taking Metoclopramide could be at increased risk for first time or worsening mental or mood changes (eg, depression) or suicidal thoughts or actions. Watch patients having Metoclopramide closely. Contact your physician simultaneously if new, worsened, or sudden symptoms including depressed mood or any unusual alteration of mood or behavior occur. Contact your physician straight away if any indications of suicidal thoughts or actions occur.

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• Metoclopramide may increase the volume of a certain hormone (prolactin) in your blood. Symptoms can sometimes include enlarged breasts, missed period, decreased sexual ability, or nipple discharge. Contact your doctor straight away should you experience some of these symptoms.

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• Lab tests, including liver and kidney function tests, could be performed while you use Metoclopramide. These tests could possibly be accustomed to monitor your problem or pay attention to unwanted side effects. Be sure to keep all doctor and lab appointments.

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• Use Metoclopramide with caution inside elderly; they may be more sensitive to its effects, especially drowsiness, confusion, and uncontrolled muscle movements, including tardive dyskinesia.

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• Metoclopramide needs to be combined with extreme caution in children; safety and effectiveness in children weren't confirmed. The probability of developing uncontrolled muscle movements might be greater in kids.

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• Pregnancy and nursing: If you get pregnant, contact your physician. You will need to discuss the benefits and risks of using Metoclopramide while you are pregnant. Metoclopramide is situated in breast milk. If you're or will probably be breast-feeding as you use Metoclopramide, consult your physician. Discuss any possible risks for your baby.

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A small number of patients have observed withdrawal symptoms when stopping Metoclopramide. These symptoms can include dizziness, nervousness, and headache.

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