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Prandin (repaglinide) is an oral diabetes medicine that can help control blood glucose levels. This medication lowers blood sugar by causing the pancreas to make insulin.

Prandin is used as well as diet and exercise to help remedy diabetes type 2. Other diabetes medicines are often utilized in combination with repaglinide if needed.

Prandin may aso supply for purposes unpublished in this medication guide.


Take Prandin exactly as prescribed by your doctor. Do not take in larger or smaller amounts and over recommended. Follow the directions on the prescription label.

Prandin is often taken 2 to 4 times daily, within half an hour before eating dinner. Follow a medical expert's instructions. If you skip a meal, don't take on your dose of Prandin. Wait until your next meal.

Your blood sugar will have to be checked often, and you might need other blood tests for your doctor's office. Visit your doctor regularly.

Know warning signs of low blood glucose (hypoglycemia) and ways to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.

Always keep a supply of sugar obtainable in case you've symptoms of low blood glucose levels. Sugar sources include orange juice, glucose gel, candy, or milk. If you have severe hypoglycemia and cannot eat or drink, readily injection of glucagon. Your doctor can give you a prescription for the glucagon emergency injection kit and tell you how to provide the injection.

Also look for indications of blood glucose levels that's too much (hyperglycemia). These symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dermititis, blurred vision, and fat loss.

Check your blood glucose levels carefully during a time of stress or illness, should you travel, exercise more than usual, drink alcohol, or skip meals. These things may affect your blood sugar levels as well as your dose needs might also change.

Your doctor might want that you stop taking Prandin for the short time in the event you get ill, have a very fever or infection, or if you have surgical procedures or a medical emergency.

Ask your doctor the way to adjust your Prandin dose if needed. Do not improve your medication dose or schedule without your medical professional's advice.

Prandin is part of a whole program of treatment this includes diet, exercise, and weight control. Follow what you eat, medication, and workout routines very closely. Changing these factors could affect your blood sugar.

Use Prandin regularly to have the most benefit. Get your prescription refilled before you run out of medication completely.





Active ingredient: Repaglinide

Repaglinide is really a white to off-white powder with molecular formula C27 H36 N2 O4 and a molecular weight of 452.6. PRANDIN tablets contain 0.5 mg, 1 mg, or 2 mg of repaglinide. In addition each tablet contains the following inactive ingredients: calcium hydrogen phosphate (anhydrous), microcrystalline cellulose, maize starch, polacrilin potassium, povidone, glycerol (85%), magnesium stearate, meglumine, and poloxamer. The 1 mg and 2 mg tablets contain iron oxides (yellow and red, respectively) as coloring agents.



Side Effects

Weight gain, diarrhea, and joint pain may occur. If all of these effects persist or worsen, notify a medical expert or pharmacist promptly.

Remember that your physician has prescribed prescription drugs as he or she has judged that the profit to you is greater than the potential risk of unwanted side effects. Many people using this medication would not have serious side effects.

Repaglinide could cause low blood sugar levels (hypoglycemia) especially should you are taking other medicines for diabetes. Consuming vast amounts of alcohol, to not get enough calories from food, or doing unusually heavy exercise can also lead to low blood glucose. Symptoms can sometimes include chills, cold sweat, dizziness, drowsiness, shaking, fast heartbeat, weakness, headache, fainting, tingling of the hands or feet, or hunger. It is really a good habit to handle glucose tablets or gel to treat low blood glucose levels. If you don't have these reliable forms of glucose, raise the blood sugar quickly when you eat an instant method to obtain sugar for example table sugar, honey, candy, or drinking a glass of veggie juice or non-diet soda. Check with your doctor or pharmacist to find out list of positive actions in case you miss a meal.

Symptoms of high blood sugar (hyperglycemia) include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, and fruity breath odor. If these symptoms occur, tell a medical expert immediately. Your doctor might need to adjust your diabetes medication(s).

A much more severe hypersensitivity for this drug is rare. However, seek immediate medical attention in case you notice any in the following signs of a serious allergic attack: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a whole list of possible negative effects. If you notice other effects unpublished above, contact your medical professional or pharmacist.


More info:

Tell your doctor about all the medications you have, especially:

cyclosporine (Gengraf, Neoral, Sandimmune);

St. John's wort;

an antibiotic like clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), or telithromycin (Ketek);

an antifungal medication such as fluconazole (Diflucan), itraconazole (Sporanox), or ketoconazole (Nizoral);

a barbiturate like phenobarbital (Solfoton);

heart or blood pressure levels medication including diltiazem (Cartia, Cardizem), nicardipine (Cardene), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), yet others;

HIV/AIDS medicine such as delavirdine (Rescriptor), efavirenz (Sustiva, Atripla), fosamprenavir (Lexiva), indinavir (Crixivan), ritonavir (Norvir), and others;

rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), or rifapentine (Priftin); or

seizure medication including carbamazepine (Carbatrol, Equetro, Tegretol), phenytoin (Dilantin), primidone (Mysoline), yet others.

You might be more likely to have hyperglycemia (high blood sugar) if you take Prandin with other drugs that raise blood glucose levels, for example:


diuretics (water pills);

steroids (prednisone and others);

phenothiazines (Compazine while others);

thyroid medicine (Synthroid among others);

birth control pills and other hormones;

seizure medicines (Dilantin among others); and

diet pills or medicines to deal with asthma, colds or allergies.

You may be very likely to have hypoglycemia (low blood sugar) should you consider other drugs that lower blood sugar, for example:

probenecid (Benemid);

a blood thinner (warfarin, Coumadin);

some nonsteroidal anti-inflammatory drugs (NSAIDs);

aspirin and other salicylates (including Pepto-Bismol);

a blood thinner (warfarin, Coumadin, Jantoven, among others);

sulfa drugs (Bactrim, Septra, Sulfatrim, SMX-TMP, and others);

a monoamine oxidase inhibitor (MAOI); or

other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos, Duetact, Actoplus Met), or rosiglitazone (Avandia, Avandaryl, Avandamet).

These lists are not complete high are many other medicines that will increase or minimizing the effects of Prandin on cutting your blood sugar. Using certain medicines can make it harder for one to tell when you've low blood sugar levels. Tell your doctor about all medications you utilize. This includes prescription, over-the-counter, vitamin, and herbal products. Do not take up a new medication without telling your physician.


Do not use Prandin in case you are allergic to repaglinide, if you've type 1 diabetes, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin). You should not use Prandin together with gemfibrozil (Lopid) or NPH insulin (including isophane insulin).

Before taking repaglinide, tell your physician or pharmacist should you are allergic with it; or if you might have any other allergies. This product might have inactive ingredients, which may cause allergies and other problems. Talk to your pharmacist for more information. 

Before using medicines, tell a medical expert or pharmacist your medical history, especially of: kidney disease, liver disease.

You may feel blurred vision, dizziness, or drowsiness on account of extremely low or high blood sugar levels. Do not drive, use machinery, or go activity that will need alertness or clear vision unless you are sure it is possible to perform such activities safely.

Limit alcohol while taking prescription drugs because it can increase potential risk of developing low blood glucose.

During points in the stress, like fever, infection, injury, or surgery, it could be harder to control your blood glucose levels. Consult a medical expert because increased stress may need changing your plan for treatment, medications, or blood sugar levels testing.

During pregnancy medicines should be used only once clearly needed. Pregnancy may cause or worsen diabetes. Discuss a plan with your medical professional for managing your blood glucose when pregnant. Your doctor may alter your diabetes treatment during your pregnancy. Discuss the hazards and benefits of different treatments (for example diet, exercise, and medications including insulin).

FDA pregnancy category C. It is not known whether Prandin will harm an child. Tell your physician in case you are pregnant or intend to become pregnant with all the Prandin. It is not known whether repaglinide passes into breast milk or if it can be unhealthy for a nursing baby. You should not breast-feed while you take Prandin.

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