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Uses

INDICATIONS

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Prandin (repaglinide) is surely an oral diabetes medicine that can help control glucose levels. This medication lowers blood glucose by causing the pancreas to produce insulin.

Prandin is used in addition to diet and exercise to help remedy diabetes type 2 symptoms. Other diabetes medicines are now and again employed in conjunction with repaglinide as needed.

Prandin may aso supply for purposes unlisted within this medication guide.

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INSTRUCTIONS  

Take Prandin exactly as prescribed by your doctor. Do not take in larger or smaller amounts or more than recommended. Follow the directions on your own prescription label.

Prandin is often taken two to four times daily, within half an hour before eating dinner. Follow your physician's instructions. If you skip dinner, don't take on your dose of Prandin. Wait until your next meal.

Your blood glucose must be checked often, and you might need other blood tests for your doctor's office. Visit your doctor regularly.

Know warning signs of low blood glucose (hypoglycemia) and ways to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.

Always keep a way to obtain sugar obtainable in case you've symptoms of low blood sugar levels. Sugar sources include orange juice, glucose gel, candy, or milk. If you might have severe hypoglycemia and cannot eat or drink, make use of an injection of glucagon. Your doctor can present you with a prescription for a glucagon emergency injection kit and let you know how to provide injection.

Also watch out for signs and symptoms of blood sugar levels that is way too high (hyperglycemia). These symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dried-out skin, blurred vision, and weight loss.

Check your blood glucose levels carefully throughout a period of stress or illness, if you travel, exercise more than usual, consume alcohol, or skip meals. These things may affect your glucose levels and your dose needs could also change.

Your doctor may wish you to stop taking Prandin to get a short time in case you get ill, use a fever or infection, or if you might have surgery or a medical emergency.

Ask your physician how to adjust your Prandin dose as needed. Do not alter your medication dose or schedule without a medical expert's advice.

Prandin is just a part of a whole program of treatment that also includes diet, exercise, and weight control. Follow your diet plan, medication, and exercise routines very closely. Changing all of these factors can impact your glucose levels.

Use Prandin regularly to find the most benefit. Get your prescription refilled before you run out of drugs completely.

DOSAGE 

 

 

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Active ingredient: Repaglinide

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Repaglinide is really a white to off-white powder with molecular formula C27 H36 N2 O4 plus a molecular weight of 452.6. PRANDIN tablets contain 0.5 mg, 1 mg, or 2 mg of repaglinide. In addition each tablet offers the following inactive ingredients: calcium hydrogen phosphate (anhydrous), microcrystalline cellulose, maize starch, polacrilin potassium, povidone, glycerol (85%), magnesium stearate, meglumine, and poloxamer. The 1 mg and a couple of mg tablets contain iron oxides (yellow and red, respectively) as coloring agents.

 

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Side Effects

Weight gain, diarrhea, and pain may occur. If some of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed prescription drugs as he or she gets judged that this benefit to you is greater than the potential risk of negative effects. Many people using prescription drugs would not have serious negative effects.

Repaglinide might cause low blood sugar (hypoglycemia) especially should you take other medicines for diabetes. Consuming bulk of alcohol, to not get enough calories from food, or doing unusually heavy exercise might also bring about low blood glucose. Symptoms may include chills, cold sweat, dizziness, drowsiness, shaking, fast heartbeat, weakness, headache, fainting, tingling in the hands or feet, or hunger. It is often a good habit to carry glucose tablets or gel to take care of low blood sugar levels. If you don't have these reliable forms of glucose, increase your blood glucose quickly when you eat an instant supply of sugar such as countertop sugar, honey, candy, or drinking a glass of fruit juice or non-diet soda. Check with your medical professional or pharmacist to learn do the following if you miss a meal.

Symptoms of high blood glucose (hyperglycemia) include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, and fruity breath odor. If these symptoms occur, tell your medical professional immediately. Your doctor may need to adjust your diabetes medication(s).

A much more severe allergic reaction to the drug is rare. However, seek immediate medical assistance in case you notice any from the following signs of a serious allergic reaction: rash, itching/swelling (especially in the face/tongue/throat), severe dizziness, trouble breathing.

This is not a total set of possible unwanted side effects. If you notice other effects unpublished above, contact a medical expert or pharmacist.

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Tell your medical professional about other medications you employ, especially:

cyclosporine (Gengraf, Neoral, Sandimmune);

St. John's wort;

an antibiotic like clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), or telithromycin (Ketek);

an antifungal medication like fluconazole (Diflucan), itraconazole (Sporanox), or ketoconazole (Nizoral);

a barbiturate like phenobarbital (Solfoton);

heart or blood pressure level medication including diltiazem (Cartia, Cardizem), nicardipine (Cardene), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), while others;

HIV/AIDS medicine including delavirdine (Rescriptor), efavirenz (Sustiva, Atripla), fosamprenavir (Lexiva), indinavir (Crixivan), ritonavir (Norvir), yet others;

rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), or rifapentine (Priftin); or

seizure medication for example carbamazepine (Carbatrol, Equetro, Tegretol), phenytoin (Dilantin), primidone (Mysoline), while others.

You might be very likely to have hyperglycemia (high blood glucose) in the event you consider Prandin along with other drugs that raise blood glucose levels, such as:

isoniazid;

diuretics (water pills);

steroids (prednisone and others);

phenothiazines (Compazine and others);

thyroid medicine (Synthroid while others);

birth control pills along with other hormones;

seizure medicines (Dilantin among others); and

diet pills or medicines to treat asthma, colds or allergies.

You may be more likely to have hypoglycemia (low blood glucose) in the event you consider other drugs that lower blood sugar, including:

probenecid (Benemid);

a blood thinner (warfarin, Coumadin);

some nonsteroidal anti-inflammatory drugs (NSAIDs);

aspirin or other salicylates (including Pepto-Bismol);

a blood thinner (warfarin, Coumadin, Jantoven, yet others);

sulfa drugs (Bactrim, Septra, Sulfatrim, SMX-TMP, among others);

a monoamine oxidase inhibitor (MAOI); or

other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos, Duetact, Actoplus Met), or rosiglitazone (Avandia, Avandaryl, Avandamet).

These lists aren't complete high a wide range of other medicines that will increase or decrease the effects of Prandin on lowering your blood sugar. Using certain medicines can make it tougher for you to definitely tell when you've low blood sugar levels. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not take up a new medication without telling your physician.

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Precautions

Do not use Prandin if you are allergic to repaglinide, if you might have type 1 diabetes, or should you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin). You should not use Prandin as well as gemfibrozil (Lopid) or NPH insulin (including isophane insulin).

Before taking repaglinide, tell your doctor or pharmacist in the event you are allergic to it; or if you've got every other allergies. This product might have inactive ingredients, which may cause allergy symptoms or other problems. Talk to your pharmacist for more details. 

Before using medicines, tell your doctor or pharmacist your health background, especially of: kidney disease, liver disease.

You may experience blurred vision, dizziness, or drowsiness as a result of extremely low or high blood sugar levels. Do not drive, use machinery, or go activity that will need alertness or clear vision until you are sure it is possible to perform such activities safely.

Limit alcohol while taking prescription drugs because it can increase potential risk of developing low blood glucose levels.

During points in the stress, for example fever, infection, injury, or surgery, it may be harder to manipulate your blood glucose levels. Consult your medical professional because increased stress may need changing your treatment solution, medications, or blood glucose testing.

During pregnancy this medication should be utilized only once clearly needed. Pregnancy may cause or worsen diabetes. Discuss a plan with a medical expert for managing your blood sugar while pregnant. Your doctor may change your diabetes treatment during your pregnancy. Discuss the potential for loss and benefits of different treatments (including diet, exercise, and medications including insulin).

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FDA pregnancy category C. It is not known whether Prandin will harm an baby. Tell a medical expert in case you are pregnant or prefer to conceive while using Prandin. It is not known whether repaglinide passes into breast milk or if maybe it's unhealthy for a nursing baby. You should not breast-feed while you are taking Prandin.

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