sinemet

Uses

This combination medication is employed to take care of signs of Parkinson's disease or Parkinson-like symptoms (such as shakiness, stiffness, difficulty moving). Parkinson's disease is thought to be caused by too little of a substance that is naturally occurringdopamine) in the brain. Levodopa modifications into dopamine in the mind, assisting to control movement. Carbidopa stops the breakdown of levodopa in the bloodstream therefore more levodopa can enter the brain. Carbidopa can additionally reduce some of levodopa's part effects such as for instance nausea and vomiting.

Exactly how to use Sinemet

Take this medication by mouth with or without food as directed by the doctor, usually three to four times each and every day.

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Using this medicine with food might help to decrease nausea. It is best to avoid a high-protein diet (it decreases the number of levodopa your body takes in) during therapy, unless directed otherwise by the doctor. Separate your dosage with this medication by because many hours as possible from any iron supplements or products containing iron (such as multivitamins with minerals) you may take. Iron can reduce the amount of this medication absorbed by the body. Consult your pharmacist or doctor for lots more details.

The dosage is situated on your condition that is medical and to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a dose that is low gradually increase your dose. Follow your physician's instructions very carefully. This combination medication comes in various strengths with various amounts of carbidopa and levodopa in each tablet. Be sure you have the correct strength of both drugs. Your doctor could also prescribe carbidopa alone to be used with this combination.

Use this medicine regularly to get the most benefit from it. Each day to help you remember, take it at the same times.

Some patients may experience a "wearing-off" (worsening of symptoms) ahead of the dose that is next due. An "on-off" impact may additionally happen, in which sudden short periods of stiffness occur. If these effects occur, contact your physician for feasible dosage adjustments that will help to lessen this effect.

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Do not stop taking this medication without consulting your medical professional. Some conditions may become even worse when this drug is quickly reduced or suddenly stopped. Your dose may gradually need to be reduced. (See also unwanted effects part.)

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Tell your medical practitioner if the condition does not improve or if it worsens.

Side Results

Dizziness, lightheadedness, sickness, vomiting, loss of appetite, trouble sleeping, uncommon dreams, or headache may take place. If some of these effects persist or worsen, tell your pharmacist or doctor quickly.

This medication may cause saliva, urine, or sweat to turn a dark color. This effect is harmless, however your clothes may be stained.

To lessen the risk of dizziness and lightheadedness, get up slowly when increasing from a sitting or lying position.

Remember that your doctor has prescribed this medication she has judged that the benefit to you is greater than the risk of side effects because he or. Many people using this medication do not have side that is serious.

Some people taking this medication have dropped asleep unexpectedly throughout their usual daily activities (such as talking on the phone, driving). In some full cases, sleep occurred without any emotions of drowsiness ahead of time. This sleep impact may occur anytime during therapy with carbidopa/levodopa regardless if you have used this medication for a time that is long. If you experience increased sleepiness or fall asleep during the day, do not drive or do other possibly dangerous activities until you have discussed this effect with your doctor. Your risk of the sleep impact is increased by making use of liquor or other medications that can make you drowsy. See also Precautions section.

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Inform your doctor immediately if you have any serious side effects, including: new/worsening movements you can't control/spasms, greatly increased eye blinking/twitching, fainting, vision changes (such as blurred vision, double vision), eye pain, severe stomach/abdominal pain, black/tarry stools, vomit that looks like coffee grounds, mental/mood changes (such as agitation, hallucinations, depression, thoughts of suicide), signs of infection (such as sore throat that doesn't go away), easy bleeding/bruising, unusual tiredness, tingling of the hands/feet, unusual strong urges (such as increased gambling, increased sexual urges).

Get help that is medical away if you have any very severe side results, including: chest pain.

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Suddenly stopping or reducing the dose of this medicine may rarely cause a very condition that is serious neuroleptic cancerous syndrome (NMS). Get medical help straight away when you yourself have any of the following symptoms: temperature, unusual muscle tightness, severe confusion, sweating, fast/irregular heartbeat, rapid breathing.

an extremely serious reaction that is allergic this drug is rare. However, get help that is medical away if you notice any symptoms of a critical sensitive reaction, including: rash, itching/swelling (especially associated with the face/tongue/throat), severe dizziness, trouble respiration.

This is maybe not a list that is complete of side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the usa -

Phone your physician for medical advice about side-effects. You may report effects that are side FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Phone your medical practitioner for medical advice about part results. You may report effects that are side Health Canada at 1-866-234-2345.

Precautions

Before taking this medication, tell your doctor or pharmacist in the event that you are allergic to carbidopa or levodopa; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergy symptoms or other problems. Talk to your pharmacist to get more details.

Before by using this medicine, tell your doctor or pharmacist your health background, especially of: liver disease, glaucoma, breathing issues (such as for instance asthma), heart disease (such as coronary attack, irregular heartbeat), kidney disease, stomach/intestinal ulcer, mental/mood disorders (such as for instance depression, schizophrenia), blood disorders, seizures, rest disorders.

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This drug might make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness you can perform such activities safely until you are sure. Limit beverages that are alcoholic. See also Side Results part.

Before having surgery, tell your doctor or dentist about most of the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when demonstrably required. Discuss the risks and benefits with your physician.

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Levodopa passes into breast milk. It really is unknown if carbidopa passes into breast milk. Check with your medical practitioner before breast-feeding.

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