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This combination medication can be used to deal with symptoms of Parkinson's disease or symptoms that are parkinson-likesuch as shakiness, stiffness, difficulty moving). Parkinson's disease is thought to be caused by too little of a substance that is naturally occurringdopamine) into the brain. Levodopa changes into dopamine in the brain, assisting to control movement. Carbidopa stops the breakdown of levodopa in the bloodstream therefore more levodopa can enter the mind. Carbidopa can additionally reduce some of levodopa's part effects such as for instance vomiting and nausea.

Exactly how to use Sinemet

Take this medication by mouth with or without meals as directed by the doctor, frequently three to four times a day.

Taking this medicine with meals might help to decrease nausea. It is best to avoid a diet that is high-proteinit decreases the amount of levodopa your body takes in) during treatment, unless directed otherwise by the doctor. Separate your dose of this medication by since many hours as possible from any iron supplements or products containing iron (such as multivitamins with minerals) you may take. Iron can reduce the amount of this medication absorbed by the body. Consult your pharmacist or doctor for lots more details.

The dosage is based on your condition that is medical and to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a dose that is low gradually increase your dose. Follow your doctor's instructions very carefully. This combination medication comes in various strengths with various amounts of carbidopa and levodopa in each tablet. Be sure you have the correct strength of both drugs. Your doctor could also prescribe carbidopa alone to be taken with this combination.

Utilize this medication regularly to get the benefit that is most from it. Each day to help you remember, take it at the same times.

Some patients may experience a "wearing-off" (worsening of symptoms) prior to the next dose is due. An "on-off" effect may also occur, in which unexpected short periods of stiffness occur. If these effects occur, contact your doctor for feasible dosage adjustments which will help to reduce this effect.

Do not stop taking this medication without consulting your medical professional. Some conditions can become even worse when this medication is quickly reduced or suddenly stopped. Your dose may need to be gradually reduced. (See also unwanted effects section.)

Inform your medical practitioner when your condition will not enhance or if it worsens.

adverse Impacts

Dizziness, lightheadedness, nausea, vomiting, loss of appetite, difficulty sleeping, unusual dreams, or headache may take place. If some of these effects persist or worsen, tell your pharmacist or doctor promptly.

This medication may cause saliva, urine, or perspiration to turn a dark color. This impact is harmless, but your clothes may be stained.

To cut back the possibility of dizziness and lightheadedness, get fully up slowly whenever increasing from a sitting or lying position.

Remember that your doctor has prescribed this medication she has judged that the benefit to you is greater than the risk of side effects because he or. Many people using this medication do not have side that is serious.

Some individuals taking this medication have fallen asleep abruptly in their usual daily activities (such as talking on the phone, driving). In some full cases, sleep occurred without any emotions of drowsiness ahead of time. This sleep impact may occur anytime during treatment with carbidopa/levodopa even when you have used this medication for a time that is long. Until you have discussed this effect with your doctor if you experience increased sleepiness or fall asleep during the day, do not drive or do other possibly dangerous activities. Your danger of the sleep effect is increased by utilizing liquor or other medicines that can cause you to drowsy. See also Precautions section.

Inform your doctor right away you can't control/spasms, greatly increased eye blinking/twitching, fainting, vision changes (such as blurred vision, double vision), eye pain, severe stomach/abdominal pain, black/tarry stools, vomit that looks like coffee grounds, mental/mood changes (such as agitation, hallucinations, depression, thoughts of suicide), signs of infection (such as sore throat that doesn't go away), easy bleeding/bruising, unusual tiredness, tingling of the hands/feet, unusual strong urges (such as increased gambling, increased sexual urges) if you have any serious adverse effects, including: new/worsening movements.

Get help that is medical away if you have actually any very serious adverse results, including: chest pain.

Suddenly stopping or reducing the dose of this medication may hardly ever cause an extremely serious condition called neuroleptic cancerous syndrome (NMS). Get medical help immediately for those who have any of the following symptoms: temperature, unusual muscle mass tightness, severe confusion, sweating, fast/irregular heartbeat, fast breathing.

an extremely serious allergic reaction to this drug is rare. However, get help that is medical away in the event that you notice any outward symptoms of a critical allergic reaction, including: rash, itching/swelling (especially associated with face/tongue/throat), serious dizziness, difficulty respiration.

This is not a list that is complete of side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the united states -

Call your doctor for medical advice about side-effects. You could report adverse effects to Food And Drug Administration at 1-800-FDA-1088 or at

In Canada - Call your medical practitioner for medical advice about side results. You may report effects that are side Health Canada at 1-866-234-2345.


Before taking this medication, tell your doctor or pharmacist in the event that you are allergic to carbidopa or levodopa; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Speak with your pharmacist to get more details.

Before applying this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, glaucoma, breathing problems (such as for example asthma), heart disease (such as for example coronary arrest, irregular heartbeat), kidney illness, stomach/intestinal ulcer, mental/mood disorders (such as for example depression, schizophrenia), blood problems, seizures, sleep disorders.

This drug might make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit beverages that are alcoholic. See also Side Results part.

Before having surgery, tell your doctor or dentist about most of the products you utilize (including prescription drugs, nonprescription drugs, and organic products).

During pregnancy, this medication should be utilized only if plainly required. Discuss the potential risks and benefits with your doctor.

Levodopa passes into breast milk. It really is unknown if carbidopa passes into breast milk. Consult with your medical practitioner before breast-feeding.

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