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• you've got uncontrolled seizures (eg, epilepsy) or loss of bowel muscle movement (paralytic ileus)

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Contact your physician or health care provider straight away if any of these connect with you.

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Some health conditions may connect to Clozaril. Tell a medical expert or pharmacist if you have any health conditions, particularly when any from the following sign up for you:

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• for those who have a history of the enlarged prostate; prolonged, painful erections; liver or kidney problems; seizures (eg, epilepsy); glaucoma; stomach or bowel obstruction; or dementia

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Some medicines may communicate with Clozaril. Tell your doctor if you take another medicines, especially any of the following:

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• Benzodiazepines (eg, lorazepam) or other medicines for mental or mood problems for the reason that probability of heart or breathing problems could possibly be increased

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• Antiarrhythmics (eg, propafenone, quinidine), anticholinergics (eg, benztropine), carbamazepine, debrisoquin, dextromethorphan, medicines for depression or high blood pressure levels, phenothiazines (eg, chlorpromazine), or tricyclic antidepressants (eg, amitriptyline) since the chance of their unwanted effects might be increased by Clozaril.

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This might not be an entire set of all interactions that will occur. Ask your doctor if Clozaril may interact with other medicines that you take. Check using your physician prior to starting, stop, or alter the dose associated with a medicine.

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Important safety information:

• Clozaril could potentially cause drowsiness, dizziness, or lightheadedness. These effects could possibly be worse if you get it with alcohol or certain medicines. Use Clozaril with caution. Do not drive or perform other possible unsafe tasks and soon you know how you respond to it.

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• Clozaril could potentially cause dizziness, lightheadedness, or fainting; alcohol, warm weather, exercise, or fever may increase these effects. To prevent them, crunches or stand slowly, especially inside the morning. Sit or lie down on the first manifestation of some of these effects.

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• Some patients who take Clozaril may develop muscle movements which they cannot control. This is more likely to happen in elderly patients, especially women. The chance this can happen or that it's going to become permanent is greater in those taking Clozaril in high doses and for quite a while. Muscle problems can also occur after short-term treatment with low doses. Tell a medical expert at the same time if you have muscle problems together with your tongue, face, mouth, jaw (eg, tongue herniated, puffing of cheeks, mouth puckering, chewing movements), arms, or legs while taking Clozaril.

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