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Precautions

 Do NOT use Colchicine if:

• you happen to be allergic to the ingredient in Colchicine

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• the patient is really a child with gout

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• you've liver or kidney problems and you're simply also taking certain other medicines (eg, atazanavir, clarithromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir or any medicine which contains ritonavir, saquinavir, telithromycin)

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Contact your physician or health care provider without delay if any of these connect with you.

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Some health concerns may talk with Colchicine . Tell your physician or pharmacist when you have any medical conditions, in particular when any with the following apply to you:

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• if you're pregnant, intending to conceive, or are breast-feeding
• if you happen to be taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

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• for those who have allergies to medicines, foods, or any other substances

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• if you have a blood disorder, stomach or bowel problems, cardiovascular disease, or liver or kidney problems, or if you are having dialysis
• if you might be in very poor health

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Some medicines may interact with Colchicine . Tell your doctor if you might be taking another medicines, especially any with the following:

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• Digoxin, fibrates (eg, fenofibric acid), gemfibrozil, or HMG-Co A reductase inhibitors (eg, simvastatin) for the reason that risk of severe or fatal muscle problems could be increased

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• Aprepitant, atazanavir, clarithromycin, cyclosporine, diltiazem, erythromycin, fluconazole, HIV protease inhibitors (eg, fosamprenavir), indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ranolazine, ritonavir or any medicine that contains ritonavir, saquinavir, telithromycin, or verapamil simply because they may increase the likelihood of Colchicine 's unwanted side effects, including severe or fatal side effects

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• Sympathomimetics (eg, pseudoephedrine, albuterol) as the chance of their unwanted effects may be increased

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This will not be an entire set of all interactions which could occur. Ask your health care provider if Colchicine may communicate with other medicines that you simply take. Check with your medical provider before starting, stop, or change the dose associated with a medicine.

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Important safety information

• Do NOT take greater than the recommended dose without checking with your medical professional.

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• Check with your doctor before you decide to use medicines that could potentially cause drowsiness (eg, sleep aids, muscle relaxers) when you are using Colchicine ; it may improve their effects. Ask your friendly phamacist in case you have questions about which medicines might cause drowsiness.

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• Colchicine may lower the ability of your body to fight infection. Avoid contact with individuals who have colds or infections. Tell a medical expert if you notice signs and symptoms of infection like fever, sore throat, rash, or chills.

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• Colchicine may slow up the variety of clot-forming cells (platelets) within your blood. Avoid activities that might cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your medical professional when you have dark, tarry, or bloody stools.

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• Accidental ingestion or overdose of Colchicine may be fatal in children and adults. Keep Colchicine out from the reach of children. In case of an overdose, call a doctor or poison control center right away.

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• If nausea, vomiting, or diarrhea occurs, ask your physician for methods to lessen these effects. Contact a medical expert right away if you experience severe or persistent diarrhea, nausea, or vomiting.

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• Tell a medical expert or dentist which you take Colchicine before you decide to receive any medical or dental care, emergency care, or surgery.

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• Rarely, Colchicine may decrease fertility in males. Discuss questions or concerns with a medical expert.

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• Colchicine may restrict certain diagnostic tests, including urine tests for red blood cells or hemoglobin. Be sure your doctor and lab personnel know you happen to be taking Colchicine .

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• Lab tests, including complete blood cell counts, kidney function, and liver function, might be performed when you use Colchicine . These tests could be used to monitor your condition or search for side effects. Be sure to keep all doctor and lab appointments.

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• Use Colchicine with caution inside elderly; they may be more sensitive to its effects, including muscle and nerve problems.

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• Colchicine ought to be in combination with careful attention in children younger 4 years; safety and effectiveness of these children weren't confirmed.
• Pregnancy and breast-feeding: If you become pregnant, contact your physician. You will need to discuss the huge benefits and perils of using Colchicine while you are pregnant. Colchicine is situated in breast milk. If you might be or will be breast-feeding as you use Colchicine , talk with your physician. Discuss any possible risks for your baby.

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