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Uses

INDICATIONS

Imuran is used in order to avoid rejection of the transplanted kidney. It is among the number of medicines called immunosuppressive agents. Azathioprine will lower your body's natural immunity in patients who receive transplants to prevent rejection from the new kidney. It is also employed to relieve pain and swelling for patients with rheumatoid arthritis.

INSTRUCTIONS

Use this medicine just as directed because of your doctor. Do not take more of it, or a reduced amount of it, than your doctor ordered. Taking a lot of might increase the chance of unwanted effects, and taking too little will not help your complaint.

This medicine is sometimes given together with other medicines. If you are using several medicines together, ensure you understand how to bring them in daytime. Ask your medical professional to help you plan a way to make sure to take your medicines at the right times.

Do not stop using this medicine without first checking with your physician.

Imuran sometimes causes feeling sick. Taking this medicine after meals or at bed time may lessen stomach upset. Talk to your doctor when you have questions or continue to have issues with feeling sick.

If you miss a dose on this medicine, go on it at the earliest opportunity. However, if it's almost time for your next dose, skip the missed dose and get back to your family dosing schedule. Do not double doses.

DOSAGE

The dose of the medicine will change for several patients. Follow your doctor's orders or the directions for the label. The following information includes just the average doses of the medicine. If your dose differs, don't put it back unless your doctor informs you for this.

The volume of medicine that you just take depends around the strength in the medicine. Also, the number of doses you are taking daily, the time allowed between doses, and also the length of time you're taking the medicine depend about the problem for which you are employing the medicine.
For oral dosage form (tablets):
For kidney transplant rejection:

For rheumatism: 

STORAGE 

Store the medicine in a closed container at room temperature, far from heat, moisture, and direct light. Keep from freezing.
Keep out from the reach of kids.
Do not keep outdated medicine or medicine no longer needed.
Ask your doctor how we should dispose of any medicine you usually do not use.

Side Effects

Along having its needed effects, medicine could cause some negative effects. Although not all of these negative effects may occur, whenever they do occur they could need medical help.

Check with your doctor immediately if any with the following negative effects occur:


More common

Rare 

Incidence unfamiliar

Some side effects may occur very often don't need medical attention. These unwanted side effects might have to go away during treatment because your body adjusts towards the medicine. Also, your quality of life care professional may be able to tell you about ways to stop or reduce many of these unwanted effects. Check using your health care professional if any from the following negative effects continue or are bothersome or if you have questions about them:
More common
Nausea or vomiting (mild)
swollen joints
Incidence unfamiliar
Hair loss or thinning in the hair

Other side effects not listed can also happen in some patients. If you notice another effects, check together with your medical practioner.

Call a medical expert for medical advice about negative effects.

Precautions

If you may be taking this medicine for some time, it is very important that your medical professional check you at regular visits for almost any problems or uncomfortable side effects which might be due to this medicine. Blood tests may be required to check for uncomfortable side effects.

Using this medicine while you're pregnant may damage your developing fetus. Use an effective kind of contraceptive to keep from conceiving a child. If you think you might have become pregnant while using the this medicine, tell your medical professional right away.

Do not employ this medicine in case you are also taking mercaptopurine (Purinethol®). Using these medicines together might cause serious unwanted side effects.

If you are choosing azathioprine for arthritis, make certain your doctor knows should you received chlorambucil (Leukeran®), cyclophosphamide (Cytoxan®, Neosar®), or melphalan (Alkeran®) to take care of your arthritis inside past. Using azathioprine after these medicines may increase your risk for unwanted side effects. Talk to a medical expert when you have questions about this.

This medicine may raise your chance of getting certain kinds of cancer, especially of the skin, lymph system (lymphoma), or blood (leukemia). Talk to a medical expert in case you have concerns relating to this risk.

Use sunscreen or sunblock lotions which has a sun-protection factor (SPF) for at least 15 on a regular basis when you might be outdoors. Wear protective clothing and hats, and turn into away from direct sunlight between the hours of 10 a.m. and 3 p.m. Avoid sunlamps and tanning beds.

While you might be undergoing treatment with azathioprine, and once you stop treatment with it, do not have any immunizations (vaccines) without your doctor's approval. Azathioprine may reduce your body's resistance along with the vaccine might not act as well or you may get the infection the vaccine is meant to stop. In addition, you shouldn't be around other persons moving into your family who receive live virus vaccines because there is a possibility they can pass herpes on you. Some examples of live vaccines include measles, mumps, influenza (nasal flu vaccine), poliovirus (oral form), rotavirus, and rubella. Do not get close to them and usually do not stay within the same room using them for days on end. If you have questions on this, talk to a medical expert.

Azathioprine can temporarily lower the quantity of white blood cells inside your blood, improving the potential for getting disease. It can also lower the amount of platelets, that happen to be essential for proper blood clotting. If this occurs, there are particular precautions you can take, specially when your blood count is low, to relieve the chance of infection or bleeding:

Check with a medical expert without delay when you have several of those symptoms while you are using this medicine: severe queasiness; diarrhea; fever; rash; a broad a feeling of discomfort or illness; muscle or joint pain; lightheadedness or dizziness; or unusual tiredness or weakness. These could be symptoms of a serious reaction towards the medicine with your bowel (intestine).

Do not take other medicines unless to remain discussed with a medical expert. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamins.


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