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Uses

INDICATIONS

Micronase (Glyburide) can be an oral diabetes medicine which enables control glucose levels.

Glyburide can be used to take care of type 2 diabetes.

This medicine is not for treating type 1 diabetes.

Glyburide may also be used for other purposes unpublished with this medication guide.

INSTRUCTIONS

Take exactly as prescribed from your doctor. Do not take in larger or smaller amounts or for more than recommended. Follow the directions on the prescription label. Your doctor may occasionally alter your dose to make sure you receive the best results.

Take glyburide together with your first meal of the day, unless a medical expert tells you otherwise.

Your blood sugar will have to be checked often, and you'll need other blood tests at your physician's office. Visit your physician regularly.
Know the warning signs of low blood sugar (hypoglycemia) and how to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.

Always keep a supply of sugar for sale in case you've signs of low blood sugar. Sugar sources include orange juice, glucose gel, candy, or milk. If you have severe hypoglycemia and cannot eat or drink, use an injection of glucagon. Your doctor can present you with a prescription for a glucagon emergency injection kit and tell you how to provide injection.

Also watch for warning signs of blood sugar that's way too high (hyperglycemia). These symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dried-out skin, blurred vision, and weight reduction.

Check your blood sugar carefully within a duration of stress or illness, should you travel, exercise more than usual, are drinking alcohol, or skip meals. These things may affect your sugar levels and your dose needs may also change.

Your doctor might want that you stop taking glyburide to get a short time in the event you get ill, possess a fever or infection, or if you have surgical procedures or a medical emergency.
Ask your physician the best way to adjust your glyburide dose as required. Do not change your medication dose or schedule without your doctor's advice.

If there are any changes in the manufacturer, strength, or kind of glyburide you use, your dosage needs may change. Always check your refills to successfully have received the correct brand name and form of medicine prescribed because of your doctor.

DOSAGE

Take as prescribed through your doctor.

STORAGE

Store at room temperature, shielded from moisture, heat, and light-weight.

MORE INFO:

Active ingredient: Glyburide

Side Effects

Stop using glyburide and get emergency medical help if you have some of these signs of a hypersensitive reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking this medication and call your physician simultaneously if you have these serious negative effects:

nausea, stomach pain, low fever, lack of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

pale skin, confusion or weakness;

easy bruising or bleeding, purple or red pinpoint spots under your skin; or

headache, trouble concentrating, memory problems, feeling unsteady, hallucinations, fainting, seizure, shallow breathing or breathing that stops.

Less serious negative effects might include:

mild nausea, heartburn, feeling full;

joint or muscle pain;

blurred vision; or

mild itching or skin rash.

This is not a complete set of side effects yet others may occur. Call your physician for medical health advice about side effects.

Precautions

You should avoid using medicines in the event you are allergic to glyburide, or:

if you are undergoing treatment with bosentan (Tracleer);

if you've type 1 diabetes; or

should you are in a state of diabetic ketoacidosis (call your physician for treatment with insulin).

To ensure you can safely take glyburide, tell your medical professional if you've any of these other difficulties:

hemolytic anemia (a lack of red blood cells);

an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);

a nerve disorder affecting bodily functions;

liver or kidney disease;

should you are allergic to sulfa drugs; or

if you've got been using insulin or taking chlorpropamide (Diabinese).

Certain oral diabetes medications may raise your probability of serious cardiovascular disease. However, not handling your diabetes damages your heart and also other organs. Talk to a medical expert about the risks and important things about your diabetes with glyburide.

FDA pregnancy category C. It is not known whether glyburide will harm an unborn baby. Similar diabetes medications have caused severe hypoglycemia in babies whose mothers had used the medication near the period of delivery. Tell your medical professional in the event you are pregnant or want to conceive with all the this medication. It is not known whether glyburide passes into breast milk or if it might harm a nursing baby.

Do not use this medication without telling your medical professional if you are breast-feeding a baby. Older adults could be prone to have low blood glucose levels while taking glyburide.

 

Important safety information:

You must avoid using prescription drugs should you are allergic to glyburide, if you are being treated with bosentan (Tracleer), if you have type 1 diabetes, or if you are in a state of diabetic ketoacidosis (call your physician for treatment with insulin).

Before taking glyburide, tell your medical professional in case you are allergic to sulfa drugs, if you've been using insulin or chlorpropamide (Diabinese), or if you've got hemolytic anemia (too little red blood cells), an enzyme deficiency (G6PD), a nerve disorder, liver disease, or kidney disease.

Take care to not let your blood sugar get too low. Low blood glucose (hypoglycemia) can occur in the event you skip a meal, exercise to much time, drink alcohol, or are under stress. Symptoms include headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating. Carry hard candy or glucose tablets along in case you've got low blood sugar levels. Other sugar sources include orange juice and milk. Be sure your loved ones and good friends know how to direct you towards an urgent situation.

Drug interactions

Tell your medical professional about other medications you use, especially:

a blood thinner for example warfarin (Coumadin, Jantoven);

cyclosporine (Gengraf, Neoral, Sandimmune);

disopyramide (Norpace);

fluconazole (Diflucan), ketoconazole (Nizoral);

fluoxetine (Prozac);

rifampin (Rifadin, Rimactane, Rifater);

an ACE inhibitor like enalapril (Vasotec), lisinopril (Prinivil, Zestril), ramipril (Altace), yet others; or

an antibiotic such as ciprofloxacin (Cipro), levofloxacin (Levaquin), among others.

Using certain medicines will make it tougher for that you tell when you've got low blood sugar. Tell a medical expert in the event you use any of the following:

albuterol (Proventil, Ventolin);

clonidine (Catapres);

reserpine; or

beta-blockers such as atenolol (Tenormin), carvedilol (Coreg), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), among others.

You could possibly be more likely to have hyperglycemia (high blood sugar) in case you take glyburide with:

isoniazid;

diuretics (water pills);

steroids (prednisone among others);

phenothiazines (Compazine yet others);

thyroid medicine (Synthroid among others);

birth control pills and also other hormones;

heart or hypertension medications (Cartia, Cardizem, Nifedical, Covera, Verelan, yet others);

niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others);

seizure medicines (Dilantin while others); and

diet pills or medicines to help remedy asthma, colds or allergies.


You may be more prone to have hypoglycemia (low blood sugar) in case you take glyburide with:

clarithromycin (Biaxin);

exenatide (Byetta);

probenecid (Benemid);

heart or blood pressure levels medication (Accupril, Altace, Lotensin, Prinivil, Vasotec, Zestril, yet others);

some nonsteroidal anti-inflammatory drugs (NSAIDs);

aspirin or other salicylates (including Pepto-Bismol);

sulfa drugs (Bactrim, Gantanol, Septra, among others);

a monoamine oxidase inhibitor (MAOI); and

other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos), or rosiglitazone (Avandia).

These lists are not complete and you'll find many other medicines that can increase or decrease the effects of glyburide on reducing your blood sugar levels. Tell your physician about all medications you have. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling a medical expert.

 


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