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Precautions

Do NOT use Paroxetine if:

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• you are allergic to any ingredient in Paroxetine

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• you consider or have got linezolid, a monoamine oxidase inhibitor (MAOI) (eg, phenelzine), selegiline, or St. John's wort within the past 14 days
• you take a fenfluramine derivative (eg, dexfenfluramine), nefazodone, pimozide, a serotonin norepinephrine reuptake inhibitor (SNRI) (eg, venlafaxine), another SSRI (eg, fluoxetine), sibutramine, thioridazine, or tryptophan.

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Contact your doctor or physician right away if any of these sign up for you.

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Some health conditions may communicate with Paroxetine. Tell your doctor or pharmacist if you have any medical ailments, particularly when any of the following connect with you:

• if you are pregnant, planning to become pregnant, or are breast-feeding

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• if you consider any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• for those who have allergies to medicines, foods, or other substances
• if you or possibly a loved one has a reputation bipolar disorder (manic-depression), other mental or mood problems, suicidal thoughts or attempts, or alcohol or substance abuse

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• if you have a history of seizures, heart problems, liver problems, severe kidney problems, stomach or bowel bleeding, narrow-angle glaucoma, diabetes, or metabolism problems

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• if you're dehydrated, have low blood sodium levels, or drink alcohol
• if you will end up having electroconvulsive therapy (ECT).

Some medicines may interact with Paroxetine. Tell your medical provider if you consider another medicines, especially any in the following:

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• Anorexiants (eg, phentermine), cimetidine, fenfluramine derivatives (eg, dexfenfluramine), linezolid, lithium, MAOIs (eg, phenelzine), metoclopramide, nefazodone, selegiline, serotonin 5-HT₁ receptor agonists (eg, sumatriptan), sibutramine, SNRIs (eg, venlafaxine), another SSRI (eg, fluoxetine), St. John's wort, tramadol, trazodone, or tryptophan because severe negative effects, say for example a reaction that will include fever, rigid muscles, hypertension changes, mental changes, confusion, irritability, agitation, delirium, or coma, may occur

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• Anticoagulants (eg, warfarin), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) as the risk of bleeding, including stomach bleeding, could possibly be increased

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• Diuretics (eg, furosemide, hydrochlorothiazide) as the risk of low blood sodium levels might be increased

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• Antiarrhythmics (eg, flecainide, propafenone, quinidine), H₁ antagonists (eg, astemizole, terfenadine), or phenothiazines (eg, chlorpromazine, thioridazine) because severe heart disease, including irregular heartbeat, may occur

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• Cyproheptadine, HIV protease inhibitors (eg, ritonavir), phenobarbital, or phenytoin because they may decrease Paroxetine's effectiveness

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• Aripiprazole, atomoxetine, clozapine, fluoxetine, pimozide, procyclidine, risperidone, theophylline, or tricyclic antidepressants (eg, amitriptyline) for the reason that probability of their unwanted side effects could be increased by Paroxetine

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• Digoxin or tamoxifen as their effectiveness could be decreased by Paroxetine.

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This might not be a total report on all interactions that will occur. Ask your medical provider if Paroxetine may talk with other medicines that you just take. Check using your doctor before you start, stop, or change the dose of any medicine.

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Important safety information:

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• Paroxetine could cause drowsiness, dizziness, or blurred vision. These effects might be worse if you go with alcohol or certain medicines. Use Paroxetine with caution. Do not drive or perform other possible unsafe tasks unless you understand how you react into it.

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• Do not are drinking alcoholic beverages while you take Paroxetine.

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• Check using your doctor before you use medicines that might cause drowsiness (eg, sleep aids, muscle relaxers) while you're using Paroxetine; it could help to increase their effects. Ask your pharmacist if you have questions regarding which medicines could cause drowsiness.

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• Several weeks may pass before your symptoms improve. Do NOT take a lot more than the recommended dose, change your dose, or use Paroxetine more than prescribed without checking with a medical expert.
• Children, teenagers, and teenagers who take Paroxetine could possibly be at increased risk for suicidal thoughts or actions. Closely watch all patients who take Paroxetine. Contact a doctor at the same time if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual difference in mood or behavior occur. Contact a doctor without delay if any signs and symptoms of suicidal thoughts or actions occur.

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• If your doctor notifys you to halt taking Paroxetine, you simply must wait for many weeks prior to starting to take certain other medicines (eg, MAOIs, nefazodone). Ask a medical expert when you should start to consider a new medicines after you've got stopped taking Paroxetine.

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• Paroxetine may rarely result in a prolonged, painful erection. This could happen even when you might be not having sex. If this just isn't treated straight away, it could possibly result in permanent sexual problems including impotence. Contact your doctor straight away in such a circumstance.
• Serotonin syndrome is a possibly fatal syndrome that may be due to Paroxetine. Your risk may be greater with Paroxetine with certain other medicines (eg, "triptans," MAOIs). Symptoms might include agitation; confusion; hallucinations; coma; fever; fast or irregular heartbeat; tremor; excessive sweating; and nausea, vomiting, or diarrhea. Contact a medical expert at the same time in case you have any one these symptoms.
• Neuroleptic malignant syndrome (NMS) can be a possibly fatal syndrome that might be brought on by Paroxetine. Your risk might be greater if Paroxetine is used with certain other medicines called antipsychotics (eg, aripiprazole, risperidone). Symptoms could possibly be comparable to serotonin syndrome and may include fever, rigid muscles, blood pressure level changes, and mental changes. Contact a medical expert immediately for those who have any of these symptoms.

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• Use Paroxetine with caution inside the elderly; they may be more understanding of its effects, especially low blood sodium levels.

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• Caution is suggested when using Paroxetine in children; they may be more sensitive to its effects, especially increased risk of suicidal thoughts and actions.

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• Paroxetine might cause weight changes. Children and teenagers may require regular weight and growth checks as they definitely take Paroxetine.
• Pregnancy and breast-feeding: Paroxetine could cause harm to the fetus. If you conceive, speak to your doctor. You will have to discuss the advantages and perils of using Paroxetine while you are pregnant. Paroxetine is found in breast milk. If you might be or will be breast-feeding as you use Paroxetine, check along with your doctor. Discuss any possible risks in your baby.

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