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Promethazine is in a group of drugs called phenothiazines (FEEN-oh-THYE-a-zeens). It works by changing the actions of chemicals within your brain. Promethazine also acts as an antihistamine. It blocks the effects from the natural chemical histamine within your body.

Promethazine is utilized to help remedy hypersensitivity including itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes.

Promethazine also prevents motion sickness, and treats nausea and vomiting or pain after surgery. It is also used like a sedative or sleep aid.

Promethazine is just not for usage for symptoms of asthma, pneumonia, and other lower respiratory tract infections.


Take promethazine just as prescribed because of your doctor. Do not take it in larger amounts and for more than recommended. Follow the directions on the prescription label.

Your doctor may occasionally alter your dose to make sure you obtain the best results from medicines.

Promethazine can be taken with or without food or milk.

Measure liquid medicine having a marked measuring spoon or medicine cup, not having a regular table spoon. If you don't possess a dose-measuring device, ask your friendly phamacist for starters.

Call your medical professional in case your symptoms don't improve, or if they become worse while taking promethazine.

This medication might cause one to have unusual results with certain medical tests. Tell any doctor who treats you you are using promethazine.

Seek emergency medical assistance if you think you have used too much of this medicine. Overdose symptoms can include severe drowsiness, dizziness, dry mouth, large pupils, flushing, nausea, vomiting, shallow breathing, and fainting.


Take it as prescribed from your doctor.


Store promethazine at room temperature from moisture, heat, and light-weight.


Active Ingredient: Promethazine



Side Effects

Get emergency medical help if you've all of these signs of a hypersensitivity: hives; difficulty breathing; swelling of your respective face, lips, tongue, or throat. Stop using promethazine and call your doctor immediately if you have these serious negative effects:

twitching, or uncontrollable movements of the eyes, lips, tongue, face, arms, or legs;

tremor (uncontrolled shaking), drooling, trouble swallowing, issues with balance or walking;

feeling restless, jittery, or agitated;

high fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid breathing;

feeling as if you might pass out;

seizure (convulsions);

pale skin, easy bruising or bleeding, fever, sore throat, flu symptoms;

decreased night vision, tunnel vision, watery eyes, increased sensitivity to light;

hallucinations, agitation;

nausea and stomach pain, skin rash, and jaundice (yellowing with the skin or eyes);

urinating under usual or otherwise at all;

joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behavior, and patchy complexion; or

slow heart rate, weak pulse, fainting, slow breathing (breathing may stop).

Less serious promethazine unwanted side effects might include:

dizziness, drowsiness, anxiety;

blurred vision, dry mouth, stuffy nose;

ringing with your ears;

weight gain, swelling within your hands or feet;

impotence, trouble through an orgasm; or


This is just not a complete list of side effects while others may occur. Tell your physician about any unusual or bothersome complication.


Stop using promethazine and call your doctor simultaneously if you might have twitching or uncontrollable movements of one's eyes, lips, tongue, face, arms, or legs. These could be early indications of dangerous unwanted side effects. Promethazine may cause unwanted effects that could impair your notions or reactions. Be careful in the event you drive or do anything whatsoever that will need one to be awake and alert. Avoid drinking alcohol, which may increase some with the unwanted effects of promethazine. There are many other medicines that could talk with promethazine. Tell your physician about every one of the prescription and over-the-counter medications you employ. This includes vitamins, minerals, herbal products, and prescriptions given by other doctors. Do not start using a new medication without telling your physician. Keep a list with you of each of the medicines you have and show this list to any doctor or another healthcare provider who treats you.

Important safety information:

Promethazine should not be presented to a child younger than two years old. Promethazine could cause severe breathing problems or death in a kid younger than 2. Carefully follow your doctor's instructions when giving this medicine to a kid of any age. Do not use this medication if you've got severe asthma, emphysema, or other breathing problem, or should you are allergic to promethazine or other phenothiazines for example chlorpromazine (Thorazine), fluphenazine (Permitil), perphenazine (Trilafon), prochlorperazine (Compazine, Compro), thioridazine (Mellaril), or trifluoperazine (Stelazine).

If you have certain conditions, you will need a dose adjustment or special tests to safely use medicines. Before you take promethazine, tell your physician if you've got:

a good seizures;

heart disease or hypertension;

liver or kidney disease;

severe asthma, emphysema, chronic obstructive pulmonary disease (COPD) or other breathing problem;

sleep apnea (breathing stops while asleep);


a stomach ulcer or digestive obstruction;

bone marrow depression;

adrenal gland tumor (pheochromocytoma);

enlarged prostate or difficulty with urination;

low levels of calcium in your blood (hypocalcemia); or

if you've ever stood a serious side-effect with all the promethazine or any other phenothiazine.

FDA pregnancy category C. It is not known whether promethazine is harmful for an unborn baby. Tell a medical expert should you are pregnant or intend to get pregnant during treatment. It is not known whether promethazine passes into breast milk or if it might harm a nursing baby. Do not use medicines without telling a medical expert in case you are breast-feeding an infant. Older adults may be more prone to have side effects from promethazine.

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