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Precautions

Do NOT use Zestoretic if:

• you're allergic to the ingredient in Zestoretic or any other sulfonamide medicine (eg, sulfamethoxazole, glyburide, probenecid)
• you possess a reputation angioedema (swelling with the face, lips, throat, or tongue)
• you use a history of kidney artery narrowing
• you cannot urinate
• you are taking dofetilide or ketanserin
• you are pregnant.

Contact your doctor or health care provider without delay if some of these affect you.

Some health concerns may connect to Zestoretic. Tell your doctor or pharmacist in case you have any medical ailments, especially if any with the following sign up for you:

• if you happen to be pregnant, planning to become pregnant, or are breast-feeding
• should you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• when you have allergies to medicines, foods, or other substances
• if you are able to become pregnant
• if you have impaired liver function, blood vessel problems (eg, stroke), heart disease (eg, congestive heart failure), or high cholesterol
• should you have a history of kidney artery narrowing or decreased kidney function, you might be on dialysis, or you've had a kidney transplant
• in case you have gout, diabetes, or electrolyte imbalances (eg, high or low potassium levels, low blood sodium levels), or you are over a sodium-restricted diet
• in the event you possess a collagen vascular disorder (eg, lupus, scleroderma), bone marrow problems, or severe defense mechanisms problems
• in the event you have a good allergies or asthma
• if you might be scheduled to possess major surgery or receive anesthesia.

Some medicines may interact with Zestoretic. Tell your doctor in the event you are taking any other medicines, especially any of the following:

• Aldosterone blockers (eg, eplerenone), corticosteroids (eg, prednisone), digoxin, dofetilide, ketanserin, lithium, loop diuretics (eg, furosemide), potassium preparations, potassium-sparing diuretics (eg, triameterene), or trimethoprim because the risk of electrolyte problems and irregular heartbeat might be increased
• Barbiturates (eg, phenobarbital), dextran sulfate, diazoxide, or narcotic pain medicine (eg, codeine) for the reason that risk of low blood pressure levels could be increased
• Gold-containing medicines (eg, sodium aurothiomalate) because flushing, nausea, vomiting, and low blood pressure may occur
• Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen, indomethacin, celecoxib) or salicylates (eg, aspirin) simply because they may decrease Zestoretic's effectiveness
• Insulin, sulfonylureas (eg, glyburide), or other medicines for diabetes (eg, metformin) as their effectiveness may be decreased by Zestoretic.

This may not be a complete set of all interactions that may occur. Ask your doctor if Zestoretic may interact with other medicines that you adopt. Check with your doctor before you begin, stop, or alter the dose associated with a medicine.

Important safety information:

• Zestoretic may cause dizziness, lightheadedness, or fainting. These effects could be worse if you adopt it with alcohol or certain medicines. Use Zestoretic with caution. Do not drive or perform other possible unsafe tasks and soon you recognize how you react into it.
• Zestoretic could potentially cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, crunch or stand slowly, especially within the morning. Sit or lie down with the first sign associated with a of these effects.
• Check with your doctor when you use a salt substitute or possibly a creation that has potassium inside it.
• Drink a lot of fluids while taking Zestoretic and prevent participating in activities that cause sweating. Dehydration, hyperhidrosis, vomiting, or diarrhea may lead to a fall in blood pressure level. Contact your medical provider simultaneously if any of these occur.
• Diabetes patients - Zestoretic may raise your blood glucose levels. High blood glucose levels might make you're feeling confused, drowsy, or thirsty. It can also cause you to be flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your medical professional without delay.
• A persistent, unproductive cough may occur. Tell your physician if this type of occurs. Recovery is rapid when the medicine is stopped.
• Patients who take medicine for high blood pressure often feel tired or run-down for some weeks after starting treatment. Be sure to take your medicine although you may may not feel "normal." Tell your doctor should you develop any new symptoms.
• Zestoretic might not exactly be well in black patients. They may also be at greater likelihood of unwanted effects. Contact your doctor if the symptoms tend not to improve or if they become worse.
• Tell your doctor or dentist that you take Zestoretic before you get any medical or dental treatments, emergency care, or surgery.
• Zestoretic might cause you to become sunburned quicker. Avoid the sun, sunlamps, or tanning booths until you understand how you answer Zestoretic. Use a sunscreen or wear protective clothing if you has to be outside for more than a short time.
• Zestoretic may interfere with certain lab tests, including parathyroid function tests. Be sure your physician and lab personnel know you are taking Zestoretic.
• Lab tests, including blood electrolytes, blood pressure, complete blood cell counts, and kidney function, could possibly be performed whilst you use Zestoretic. These tests could be used to monitor your condition or look for negative effects. Be sure to keep all doctor and lab appointments.
• Use Zestoretic with caution inside elderly; they could be more understanding of its effects.
• Zestoretic ought to be in combination with extreme caution in kids; safety and effectiveness in kids are not confirmed.
• Pregnancy and breast-feeding: Zestoretic could potentially cause birth defects or fetal death if you are taking it while you are pregnant. If you think you may be pregnant, get hold of your doctor right away. Zestoretic is located in breast milk. Do not breastfeed while taking Zestoretic.